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View Structure Prediction Details

Protein: wrm-1
Organism: Caenorhabditis elegans
Length: 796 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wrm-1.

Description E-value Query
Range
Subject
Range
gi|7494869 - gi|7494869|pir||T15342 hypothetical protein B0336.1 - Caenorhabditis elegans
501.0 [0..1] [775..144]

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Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVDCAETFS QPCTPLNFNP MTPSTSRVST PVRPSSTMSA RQYSGSPFKA QPQNMEPSNS  60
   61 RVQELREAAV GKRSYTNAWM QGTYAPPQMA GQQQRFSRPP SVIGSTMSHM T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [112-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMSEMTAYSY GGLSMLSVNT EMGEFNNFVN QAPYQRALTR VSQVSENQDP TNRQYPMTAP  60
   61 EIIENLESTE LINQAAAIRA LEPIVKAGGM LQTWGPK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 83.0
Match: 1wa5B
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [209-796]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAEPIIRALF QVLIPRPVEN ENVIRKAFEI LHHSILLSNK EIRRIDRMFF RLNAALMDPN  60
   61 GPPVFNVPKP YSIYEIVMTR AIQLDTKFES SAMVLLVHLC CKPHFMKIFF GEDETQQSPA 120
  121 HRRLHKIVIE FAIGNLRRPE TKSKNKGLCV SIIKNLSNKN ATIKDMSERL GVVSLFHQIM 180
  181 QNEVIHEDLL WSTMQALTVF CGDVKNGTHF VQMGGAQVLC GLLSHGSTRL LHELLKCLRR 240
  241 VSDLPAIQEQ DMKESIHCIV QLIGCSDVTI VELATGTLRN IGLHNKMNKA FMVQDGVTSH 300
  301 AIAVLRTSEQ FTYQPHANID LYRKQILSIY ENCLSVLNNV TSMAPQDIKE SAVSACRMIS 360
  361 ENADSAYVLL HYFNVGNRKC RKLAVTVMKR VIETVPAFAD PFVDLLGTTN EPLPILLLQR 420
  421 AFQSLDEWRK TSVEMMNCDG RSAEQRRELD DRRKDHEDIV KRSVGLLTNL CSQANPRFFH 480
  481 SLKLVLTNGT LNPFQWLTHE MSDGILQEWL AFILSICSRD ESLQTFMMYR FLEQAKMTEA 540
  541 FFAELKARRQ NSNIQTMLSK IIDLGRHQQR IVSQQHQQHQ MQHHRQLM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.09691
Match: 1jpwA
Description: beta-Catenin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.5792930989505 bayes_pls_golite062009
protein transporter activity 1.46178231098581 bayes_pls_golite062009
protein binding 1.041337870941 bayes_pls_golite062009
transporter activity 0.53053318170156 bayes_pls_golite062009
substrate-specific transporter activity 0.11990405994399 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle