Protein Overview: msh-5

General Information:
Name(s) found:	msh-5 / CE26678 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00003421 locus:msh-5 MutS protein homolog 5 status:Confirmed UniProt:Q19272 protein_id:CAA98059.2 [WormBase] gi\|8515837\|gb\|AAF76200.1\| MSH-5 [Caenorhabditis elegans] [NCBI NR] gi\|52783755\|sp\|Q19272.2\|MSH5_CAEEL RecName: Full=MutS protein homolog 5 [NCBI NR] gi\|17539736\|ref\|NP_502531.1\| MSH (MutS Homolog) family member (msh-5) [Caenorhabditis elegans] [NCBI NR] gi\|13548316\|emb\|CAA98059.2\| C. elegans protein F09E8.3, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] MutS protein homolog 5 OS=Caenorhabditis elegans GN=msh-5 PE=2 SV=2 [Swiss-Prot] [wormpep67.fasta] CE26678 WBGene00003421 locus:msh-5 Yeast DNA mismatch repair protein MSH5 like status:Confirmed SW:Q19272 protein_id:CAA98059.2 [wormpep150.fasta] 26678 WBGene00003421 locus:msh-5 Yeast DNA mismatch repair protein MSH5 like status:Confirmed SW:Q19272 protein_id:CAA98059.2 [wormpep130-phg-ecoli-orf-rand.fasta] MutS Homolog, germline specific DNA mismatch repair protein required for crossing over and chiasma formation (153.1 kD) (msh-5) [Caenorhabditis elegans]gi\|13548316\|emb\|CAA98059.2\| Hypothetical protein F09E8.3 [Caenorhabditis elegans]gi\|8515837\|gb\|AAF762 [nrdb_11152004_Chlamydomonas] locus:msh-5 Yeast DNA mismatch repair protein MSH5 like status:Confirmed SW:Q19272 protein_id:CAA98059.2 [wormpep115.fasta.reversed] CE26678 locus:msh-5 Yeast DNA mismatch repair protein MSH5 like status:Confirmed SW:Q19272 protein_id:CAA98059.2 [wormpep80.hongbin] CE26678 WBGene00003421 locus:msh-5 Yeast DNA mismatch repair protein MSH5 like status:Confirmed UniProt:Q19272 protein_id:CAA98059.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE26678 WBGene00003421 locus:msh-5 Yeast DNA mismatch repair protein MSH5 like status:Confirmed UniProt:Q19272 protein_id:CAA98059.2\| [wormORF-contam.fasta] Hypothetical protein F09E8.3 [Caenorhabditis elegans] [nr-271106-contam.fasta] MutS protein homolog 5 [nr-271106-contam.fasta] MSH (MutS Homolog) family member (msh-5) [Caenorhabditis elegans] [nr-271106-contam.fasta] MSH-5 [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE26678 WBGene00003421 locus:msh-5 status:Confirmed UniProt:Q19272 protein_id:CAA98059.2 MutS protein homolog 5 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1369 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA] MutSalpha complex [IEA] MutSbeta complex [IEA]
Biological Process:	chiasma assembly [IMP] reciprocal meiotic recombination [IMP] embryonic development ending in birth or egg hatching [IMP] homologous chromosome segregation [IMP] maintenance of fidelity involved in DNA-dependent DNA replication [IEA] mismatch repair [IEA]
Molecular Function:	ATP binding [IEA] DNA binding [IEA] mismatched DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTRWRYYNS KRGNGFRGRG RGRGRGTSLT AVALPRDDNF HKGAQDGAYF KDMPMDPEQF  60
   61 RDETVLSLSF AQGMLGAAYY EQSSQLLKIM NDISEDLEFR FLKRLIDDVK PTLIIANRSQ 120
  121 DLEFIKFLTT RYDPQEKIYE DGTTEEGTSE DTVPTWDSSL AYSTDETTAE KEEKEEDEDD 180
  181 DDEGLPAKLN KLPNNFFRMS RAIERLKAMA GSHDSSMTEE DKYIIIKMRF DIEAVNMIRS 240
  241 FGALLLFLDE TRMGVTDDPL SVTSPIKSIK TFTLGNLVEI DFNTIQALDI LPKETENKKT 300
  301 FGQGRSLYQL MDKCRSTVGK KCLRKWFRNP TTDRDDLVSR QKCVHYFKQD WNAEVTAKLS 360
  361 SILGRVKALN SVFQKFQSGT AQLIHWECFV STVNALVEIL NIIRQTPISK EFPVESDLLR 420
  421 EVSEIAVIAG SIINFAESKI QGRVTVMNGI DEELDEIRDT YENMPMVLTA IAKQEEARLG 480
  481 LPPYSNVACV YIPLVGFVLS VPRDYGVESQ PDMTLLYSTH EDLRVRNATT SRLDDEFGDI 540
  541 LMRLIDSQTA IILTLKTRVM KKKRSIIKLL SIASRIDVLI SFGLIAAQNG WNCPALVDEP 600
  601 VIEAVELYHP ISVLVVKKSF VPNQVSSGRD GIKASIITGP NACGKSVYMK SIGIMVFLSH 660
  661 IGSFVPARHA KIGIVDRIVT RMFTVDSVLD GMSTFAKDVE QVALALRKAT GNSLVIIDEF 720
  721 GKGTMTEVGL SLLASVMTYW MNRGADRCPH IFLSSHFHAL PNYIPLETNI ATFLTFTVLR 780
  781 EAGGKIKYLF RMTPGLVDCS FALSVAKEEG IPPPVIGRAC RIYKALKAGT LLKEIKAEVS 840
  841 NDNEKQLVED MDVVLADEDG FMAAVESFVK RKKTSFCESS MRNVSEEIEK ERSEASTPAS 900
  901 KSRSTITARS NSVLSSRSMA SVDQLSVLDA LLPKKKKKKV TGSSMESSMS PDPFQEEDEG 960
  961 TEGEEDQISA PVSRPTLPSV QKYASEEEKQ QSINSRHSFS TRTAIHIPTP IQMGEAGGVK1020
 1021 RPRSTSTSSP GPSASKSVRT EVFKKTPNVK ESQVLETPKQ LSISSFLEPK FPSSEKDVIS1080
 1081 RVSERYLQSD PFKTPISDRR SQQSSRHSTP KNRSMNQSLI QSARDTPHET IRSSNEVNPE1140
 1141 FFNIFNFPDD SILKSQDTYD PNVTPRSSSR RELRPDVSHS QNSQFGEVFS ELGTQFSIFN1200
 1201 SQQSFPGNSM GTTNPDCSIF DDFFANSQDG EKKIDSTKTS MPIVNSDNFI FKTPEPRSSE1260
 1261 KQRSLLKNKG QASNSSISPS SLILGQLAFG DVDQTPRPRG DNPIEFQYDV VDDDDPIFEE1320
 1321 KNCSAPVFEF LKSNDDEEDD EFLKSFLETE GSLHIDTSAD ETIDRSKRS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.92

Protein Overview: msh-5

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: