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Protein Overview: glh-1

General Information:
Name(s) found: glh-1 / CE25121 [WormBase]
Description(s) found:
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  • WBGene00001598 locus:glh-1 ATP-dependent RNA helicase glh-1 status:Confirmed UniProt:P34689 protein_id:CCD67591.1 [WormBase]
  • gi|51338772|sp|P34689.3|GLH1_CAEEL RecName: Full=ATP-dependent RNA helicase glh-1; AltName: Full=Germline helicase 1 [NCBI NR]
  • gi|17507877|ref|NP_491963.1| Germ-Line Helicase family member (glh-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|14625283|gb|AAB52901.2| Germ-line helicase protein 1 [Caenorhabditis elegans] [NCBI NR]
  • ATP-dependent RNA helicase glh-1 OS=Caenorhabditis elegans GN=glh-1 PE=1 SV=3 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE25121 WBGene00001598 locus:glh-1 RNA helicase status:Confirmed SW:P34689 protein_id:AAB52901.2 [wormpep150.fasta]
  • 25121 WBGene00001598 locus:glh-1 RNA helicase status:Confirmed TR:Q7KQH5 protein_id:AAB52901.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • Germ-Line Helicase GLH-1, Germline RNA helicase (79.8 kD) (glh-1) [Caenorhabditis elegans]gi|14625283|gb|AAB52901.2| Germ-line helicase protein 1 [Caenorhabditis elegans]gi|51338772|sp|P34689|GLH1_CAEEL ATP-dependent RNA helicase glh-1 (Germline helicas [nrdb_11152004_Chlamydomonas]
  • 25121 WBGene00001598 locus:glh-1 RNA helicase status:Confirmed SW:P34689 protein_id:AAB52901.2 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:glh-1 RNA helicase status:Confirmed TN:AAB52901 protein_id:AAB52901.2 [wormpep115.fasta.reversed]
  • CE25121 locus:glh-1 RNA helicase status:Confirmed [wormpep80.hongbin]
  • CE25121 WBGene00001598 locus:glh-1 RNA helicase status:Confirmed UniProt:P34689 protein_id:AAB52901.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE25121 WBGene00001598 locus:glh-1 RNA helicase status:Confirmed UniProt:P34689 protein_id:AAB52901.2| [wormORF-contam.fasta]
  • Germ-Line Helicase family member (glh-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Germ-line helicase protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • ATP-dependent RNA helicase glh-1 (Germline helicase 1) [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE25121 WBGene00001598 locus:glh-1 RNA helicase status:Confirmed UniProt:P34689 protein_id:CCD67591.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE25121 WBGene00001598 locus:glh-1 status:Confirmed UniProt:P34689 protein_id:CCD67591.1 ATP-dependent RNA helicase glh-1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 763 amino acids

    Gene Ontology:
    Cellular Component: P granule [IDALink to PubMed article]
    Biological Process: germ cell development [IMPLink to PubMed article]
    RNA metabolic process [ISSLink to PubMed article]
    post-embryonic development [IMPLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    protein binding [IPILink to PubMed article]
    RNA helicase activity [IDALink to PubMed article]
    DEAD/H-box RNA helicase binding [IPILink to PubMed article]
    ATP-dependent helicase activity [IEALink to PubMed article]
    JUN kinase binding [IPILink to PubMed article]
    helicase activity [IEALink to PubMed article]
    protein self-association [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDGWSDSES AAKAKTGFGS GGGFGGGNNG GSGFGGGKNG GTGFGGGNTG GSGFGGGNTG  60
   61 GSGFGGGKTG GSGFGGGNTC GSGFGGGSTG GSPYGGASSG FGGSTATSGF GSGEKSSAFG 120
  121 GSGGFGGSAT GFGSGGGSFG GGNSGFGEGG HGGGERNNNC FNCQQPGHRS SDCPEPRKER 180
  181 EPRVCYNCQQ PGHTSRECTE ERKPREGRTG GFGGGAGFGN NGGNDGFGGD GGFGGGEERG 240
  241 PMKCFNCKGE GHRSAECPEP PRGCFNCGEQ GHRSNECPNP AKPREGVEGE GPKATYVPVE 300
  301 DNMEDVFNMQ KISEGLMFNK FFDAEVKLTS SEKTVGIKPC KTFAEANLTE TMQKNVAHAG 360
  361 YSKTTPIQQY ALPLVHQGYD IMACAQTGSG KTAAFLLPIM TRLIDDNNLN TAGEGGCYPR 420
  421 CIILTPTREL ADQIYNEGRK FAYQTMMEIK PVYGGLAVGY NKGQIEKGAT IIVGTVGRIK 480
  481 HFCEEGTIKL DKCRFFVLDE ADRMIDAMGF GTDIETIVNY DSMPRKENRQ TLMFSATFPD 540
  541 SVQEAARAFL RENYVMIAID KIGAANKCVL QEFERCERSE KKDKLLELLG IDIDSYTTEK 600
  601 SAEVYTKKTM VFVSQRAMAD TLASILSSAQ VPAITIHGAR EQRERSEALR QFRNGSKPVL 660
  661 IATAVAERGL DIKGVDHVIN YDMPDNIDDY IHRIGRTGRV GNSGRATSFI SEDCSLLSEL 720
  721 VGVLADAQQI VPDWMQGAAG GNYGASGFGS SVPTQVPQDE EGW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..220] PSI-BLAST 5.221849 No description for 1y0fB was found.
    2 View Details [221..286] deduced N/A No confident structure predictions are available.
    3 View Details [287..763] PSI-BLAST 107.0 No description for 2db3A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle