Protein Overview: ced-5

General Information:
Name(s) found:	ced-5 / CE24779 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00000419 locus:ced-5 status:Confirmed UniProt:G5EEN3 protein_id:CAB60991.1 [WormBase] gi\|6434274\|emb\|CAB61006.1\| C. elegans protein C02F4.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|6434254\|emb\|CAB60991.1\| C. elegans protein C02F4.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|3015623\|gb\|AAC38973.1\| CED-5 [Caenorhabditis elegans] [NCBI NR] gi\|17538408\|ref\|NP_501938.1\| CEll Death abnormality family member (ced-5) [Caenorhabditis elegans] [NCBI NR] [wormpep67.fasta] CE24779 WBGene00000419 locus:ced-5 DOCK180 protein status:Confirmed TR:O17758 protein_id:CAB61006.1 [wormpep150.fasta] 24779 WBGene00000419 locus:ced-5 DOCK180 protein status:Confirmed TR:O17758 protein_id:CAB61006.1 [wormpep130-phg-ecoli-orf-rand.fasta] CEll Death abnormality CED-5, cell corpse engulfment protein, similar to human major CRK-binding protein DOCK180, dedicator of cytokinesis (203.8 kD) (ced-5) [Caenorhabditis elegans]gi\|6434274\|emb\|CAB61006.1\| Hypothetical protein C02F4.1 [Caenorhabditis [nrdb_11152004_Chlamydomonas] locus:ced-5 DOCK180 protein status:Confirmed TR:O17758 protein_id:CAB61006.1 [wormpep115.fasta.reversed] CE24779 locus:ced-5 DOCK180 protein status:Confirmed TR:O17758 protein_id:CAB61006.1 [wormpep80.hongbin] CE24779 WBGene00000419 locus:ced-5 DOCK180 protein status:Confirmed UniProt:O17758_CAEEL protein_id:CAB61006.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE24779 WBGene00000419 locus:ced-5 DOCK180 protein status:Confirmed UniProt:O17758_CAEEL protein_id:CAB61006.1\| [wormORF-contam.fasta] Hypothetical protein C02F4.1 [Caenorhabditis elegans] [nr-271106-contam.fasta] CED-5 [Caenorhabditis elegans] [nr-271106-contam.fasta] CEll Death abnormality family member (ced-5) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE24779 WBGene00000419 locus:ced-5 DOCK180 protein status:Confirmed UniProt:O17758 protein_id:CAB61006.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE24779 WBGene00000419 locus:ced-5 DOCK180 protein status:Confirmed UniProt:G5EEN3 protein_id:CAB60991.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE24779 WBGene00000419 locus:ced-5 status:Confirmed UniProt:G5EEN3 protein_id:CAB60991.1 [wormpep246-ecoli-contam.fasta] CED-5 OS=Caenorhabditis elegans GN=ced-5 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	1781 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [TAS]
Biological Process:	engulfment of apoptotic cell [IMP] cell migration [IMP]
Molecular Function:	small GTPase regulator activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTGFYYAI VQYTFEDPLP SCDAPRLELF IGDRICVYGQ HGEWGYGRKF DEKNGKCGIF  60
   61 PLAYVQIVQK SMFVSTSDGY LVVDEISRVI NEWWTKIKEL MVETTRIGSF EDLMDSFNEL 120
  121 LIIKTKIESG GIPIEELSKL RLRVSKLVDR GNTILGQDVV IRNEEGVPLD VESLSLLRTY 180
  181 EAHISSKGRV GSLMREKPEN VTINDSFSLL LSIKSVELHC KYSCEISISL YDLDKKMFTT 240
  241 DSYTFLWNSG SGKHTDLNLK ALFTDFAKED IQKKYLMVTR VVHVSPIESS NATMRKHGHH 300
  301 EATIPKTFYC RQSYASDIME MSSIFLAGVG HEAKERVIFL NREPELPLSL KAYHATNRIP 360
  361 KNLSNDMETK LLISTQLVPG NVSQIKARHP HLFSRCPAAI LRRADRTAVS IEDSRNEMYI 420
  421 TLMQAELSGK SSDRNIEARL HVVESNGHVM ENVFETISVT GSQLSTVYKS IVVYHTDKPM 480
  481 WTEPIKIALP SCASHDVYLR ILFYSKKAYD KPKPEKGPFA IAHVQLIRSS ALLCDGEHDL 540
  541 AVYKIDNPGS HFDESNVHYM NLPDTRRTLK ESIGSAKPHS QGFSLSDKSF VMISTHSCSS 600
  601 MLTQNEHLLN VLRWRVNCVN LTSSLVALAQ PIGDTEHEMI RFFSHLLDAL FEIWHDRETS 660
  661 EKVVFDVIVA VLRICEEPRH YPQAAKIFEV YLKRFSFTSA ALKILKCLNH YVISDSEDSN 720
  721 EKARNAFKVM GPLFKLVVVS KKCGIKFEEF DDFEKTYKQY LREFMKSLVA LMSEKKAKMT 780
  781 VQNTALKSIP TIIDLLNESD SVSPENLCGF IVDLMNNFGS NIVTRERLNF IAQIVETRFF 840
  841 SLSICREQLL IPCLQIALDI IQIDNMATEK GEFADRAAEC ASIIAAILER LFADAKSGEG 900
  901 NAERELTSFI LMVYRPLVQA MIRVIHDDKH TDDDARGHFF SVILALLDKM SAQMFSEYVE 960
  961 ERSSDIDKRD FLMEMVQMIR DLLNRNAFPS TWKDMIMLQN KVIHKSLRFV MSAVQTFFSN1020
 1021 DKFCVEMWRE YMVTVVSFVT QEGLNSKHEW MKNEDEDMRI QLRKAAAKDL RSMWFRLTPS1080
 1081 QKLNYIPSMI GSFLKVSLVD DDETREATIP IFFDMMQTEY NTSASRSFTE FASELVSQLD1140
 1141 TNVDQHSATK GFKEHFRQLS ITLCQSDKEL MANGGEELIE RIDRLLTALI EYHEVASKSL1200
 1201 VECVDSLMSR TVQLMRYYNQ YSHKELYVKY IYKLYDLHTS YGNKIEAAKT LLRHATMLTF1260
 1261 DDDALPQWLI ARSLNRHREL HRQLKEDLME EAGNLFSKGE DWEDALIVYN QLVPVYQNII1320
 1321 MDYDKLAGLL QKIAQLYTSI SRTERAYFYY YLVAFYGQGF PAYLNGHKFV FRSEKLEMHG1380
 1381 EFMQRIMKMY DNPEKIMKTD PCPHLVDSPG RYIQVFNIDP IGTGCSFENN PEVKPVIKKY1440
 1441 FRYYNIQTFE YSKVEERKDT KWTSIDPSSE FMRNWLVRRR IKTADSLPTD LRFTEIVELS1500
 1501 DPIYVTPLQN AVEQMRKKNK ELNETAASAE SNPNFDLKLL SRDILGVVSA AVMGGVKNYE1560
 1561 VFFTEACRNI CECGEQSVIM ELSSLIIEQV EILEYCCYVH ASRCQGEARA INTMLADSFD1620
 1621 SHRRYVEENF GKTRSRLPTH ANIRLSSFDS DSINDGMMTM KSGKAAVLGN AVANLIYSNK1680
 1681 RSSGPGTPVN LSSRSAPSFD NISSKLRSSL AISKLAPPPR PPNPISPINR GPSSNYEGIR1740
 1741 MRAHSHQAST VSLNHMSVAP PLPPRPDRPD MDPNRTLKRK N

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: ced-5

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: