Protein Overview: unc-51

General Information:
Name(s) found:	unc-51 / CE24516 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006786 locus:unc-51 Serine\/threonine-protein kinase unc-51 status:Confirmed UniProt:Q23023 protein_id:CAB60406.1 [WormBase] gi\|6425373\|emb\|CAB60406.1\| C. elegans protein Y60A3A.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|558375\|emb\|CAA86114.1\| serine/threonine kinase [Caenorhabditis elegans] [NCBI NR] gi\|2499617\|sp\|Q23023.1\|UNC51_CAEEL RecName: Full=Serine/threonine-protein kinase unc-51; AltName: Full=Uncoordinated protein 51 [NCBI NR] gi\|17564910\|ref\|NP_507869.1\| UNCoordinated family member (unc-51) [Caenorhabditis elegans] [NCBI NR] pir\|\|T43631 serine/threonine kinase - Caenorhabditis elegans [NCBI NR] gi\|1091677\|prf\|\|2021343A Ser/Thr kinase [NCBI NR] Serine/threonine-protein kinase unc-51 OS=Caenorhabditis elegans GN=unc-51 PE=1 SV=1 [Swiss-Prot] (Q23023) Serine/threonine-protein kinase unc-51 (EC 2.7.1.37) (Uncoordinated protein 51) [Swiss-Prot] [wormpep67.fasta] CE24516 WBGene00006786 locus:unc-51 serine\/threonine protein kinase status:Confirmed SW:Q23023 protein_id:CAB60406.1 [wormpep150.fasta] 24516 WBGene00006786 locus:unc-51 serine\/threonine protein kinase status:Confirmed SW:Q23023 protein_id:CAB60406.1 [wormpep130-phg-ecoli-orf-rand.fasta] UNCoordinated locomotion UNC-51, serine/threonine kinase (94.9 kD) (unc-51) [Caenorhabditis elegans]gi\|6425373\|emb\|CAB60406.1\| Hypothetical protein Y60A3A.1 [Caenorhabditis elegans]gi\|11346405\|pir\|\|T43631 serine/threonine kinase - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas] locus:unc-51 serine\/threonine protein kinase status:Confirmed SW:Q23023 protein_id:CAB60406.1 [wormpep115.fasta.reversed] CE24516 locus:unc-51 serine\/threonine protein kinase status:Confirmed SW:Q23023 protein_id:CAB60406.1 [wormpep80.hongbin] CE24516 WBGene00006786 locus:unc-51 serine\/threonine protein kinase status:Confirmed UniProt:UNC51_CAEEL protein_id:CAB60406.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE24516 WBGene00006786 locus:unc-51 serine\/threonine protein kinase status:Confirmed UniProt:UNC51_CAEEL protein_id:CAB60406.1\| [wormORF-contam.fasta] Ser/Thr kinase [nr-271106-contam.fasta] serine/threonine kinase [Caenorhabditis elegans] [nr-271106-contam.fasta] Serine/threonine-protein kinase unc-51 (Uncoordinated protein 51) [nr-271106-contam.fasta] Hypothetical protein Y60A3A.1 [Caenorhabditis elegans] [nr-271106-contam.fasta] UNCoordinated family member (unc-51) [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE24516 WBGene00006786 locus:unc-51 serine\/threonine protein kinase status:Confirmed UniProt:Q23023 protein_id:CAB60406.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] CE24516 WBGene00006786 locus:unc-51 status:Confirmed UniProt:Q23023 protein_id:CAB60406.1 Serine\/threonine-protein kinase unc-51 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	856 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	regulation of axon extension [IMP] dauer larval development [IGI] axonogenesis [IMP] autophagy [IGI] axon guidance [IMP] protein amino acid phosphorylation [IEA] cell migration [IMP]
Molecular Function:	magnesium ion binding [IEA] ATP binding [IEA] protein tyrosine kinase activity [IEA] protein kinase activity [IEA] protein serine/threonine kinase activity [IEA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQFDGFEYS KRDLLGHGAF AIVYRGRYVD RTDVPVAIKA IAKKNISKSK NLLTKEIKIL  60
   61 KELSSLKHEN LVGLLKCTET PTHVYLVMEF CNGGDLADYL QQKTTLNEDT IQHFVVQIAH 120
  121 ALEAINKKGI VHRDLKPQNI LLCNNSRTQN PHFTDIVIKL ADFGFARFLN DGVMAATLCG 180
  181 SPMYMAPEVI MSMQYDAKAD LWSIGTILFQ CLTGKAPFVA QTPPQLKAYY EKTRELRPNI 240
  241 PEWCSPNLRD LLLRLLKRNA KDRISFEDFF NHPFLTSPLL PSPSKRILES ARSPLLANRR 300
  301 IITPQSSLPV PKRAGSTKLD SPTPVRRIGE SPRVQRRVIT PGMPSPVPGA PMQESTDFTF 360
  361 LPPRQESSPV KQVQVHTNVS PSLTTCKPVP VPSQRLTYQK MEERLAAARK TAVPSSSSPT 420
  421 GSAVSAQHQH QHQQQQEPAS SPVVQRIERP DQLPRRTTLQ DPNAHDIERM TMPNPTFVVC 480
  481 GSSTKPSPNN ANRVRRSTIT SPADTQDMVA ADQMLSNLDP TTTTTTIPKS ATTANIQGIP 540
  541 RGARDRSVTS PPQPTIHENE PLDNAKYQQT DVNNSPTAPT EPFIIKNQTT CSTSSTSSSV 600
  601 VEEEEAMSLP FASGSHLAAG FKKTPAEVPM DHGALPPALD QEIVLGEEHK QILAKLRFVA 660
  661 ELVDTLIHVA EQKDNPLASA MASRRQLLTT GTSTTNTSSP YRRAEQLVVY VRALHMLSSA 720
  721 LLLAQTNVAN RVLHPSVAVQ QVLNQLNDKY HQCLVRSQEL ASLGLPGQDP AMAVISAERI 780
  781 MYRHAIELCQ AAALDELFGN PQLCSQRYQT AYMMLHTLAE QVNCDQDKTV LTRYKVAVEK 840
  841 RLRILERQGF VAAVNT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: unc-51

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: