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Protein Overview: CE24222

General Information:
Name(s) found: CE24222 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00012608 Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial status:Confirmed UniProt:Q9U2M4 protein_id:CAA21631.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 465 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEALink to PubMed article]
    alcohol metabolic process [IEALink to PubMed article]
    carbon utilization [IEALink to PubMed article]
    Molecular Function: oxidoreductase activity [IEALink to PubMed article]
    metal ion binding [IEALink to PubMed article]
    acetaldehyde dehydrogenase (acetylating) activity [IEALink to PubMed article]
    alcohol dehydrogenase (NAD) activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASLARGIL SKMGGSCCPH HAPATNPFKL AKLHGNNKST DYAFEMVCST LRFGKGVTLE  60
   61 IGYDVRNLGA KKTLLITDKN VQNTIAFKNA EQALKMVNIE YEVFDDVLIE PTVNSMQKAI 120
  121 AFAKSKQFDS FIAVGGGSVI DTTKAAALYA SNPEADFLDF VGPPFGKSMQ PKNPMLPLIA 180
  181 VPTTAGTGSE TTAAAIMDLP EHKCKTGIRL RCIKPYLAVV DPLNVMSMPR NVAIYSGFDV 240
  241 LCHALESFTA LPFDQRSPRP ENPGVRPLYQ GSNPISDVWS KEALRIIGKY FRRSIFDPTD 300
  301 EEARTEMLKA SSFAGIGFGN AGVHLCHGLS YPISSQAKSC VADDYPKEKN LIPHGLSVMT 360
  361 TAVADFEFTT AACPDRHLIS AQTLGADIPN NASNEYISRT LCDRLRGYMR DFGVPNGLKG 420
  421 MGFEFSDIEM LTEAASHSVP NIAISPKSAD REIISTLYEK SLTVY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..465] PSI-BLAST 87.69897 Crystal Structure of Lactaldehyde reductase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydroxyacid-oxoacid transhydrogenase activity
    		•  8.51876704052427 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  4.00011629375661 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.07409531087588 bayes_pls_golite062009
  • alcohol dehydrogenase activity, metal ion-independent
    		•  3.05722501802075 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.83823088483915 bayes_pls_golite062009
  • catalytic activity
    		•  2.37357608468991 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  2.10085302216488 bayes_pls_golite062009
  • binding
    		•  1.15096180564234 bayes_pls_golite062009
  • 3-chloroallyl aldehyde dehydrogenase activity
    		•  0.831155115586418 bayes_pls_golite062009
  • cation binding
    		•  0.319000821544479 bayes_pls_golite062009
  • metal ion binding
    		•  0.319000821544479 bayes_pls_golite062009
  • ion binding
    		•  0.313606245452103 bayes_pls_golite062009
  • protein binding
    		•  0.295023706645045 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.259889634539407 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.0904828025133766 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle