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View Structure Prediction Details

Protein: CE24222
Organism: Caenorhabditis elegans
Length: 465 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE24222.

Description E-value Query
Range
Subject
Range
gi|241903602, gi... - gi|241903602|ref|ZP_04788323.1| iron-containing alcohol dehydrogenase [Thermoanaerobacter brockii su...
gi|76588428, gi|... - gi|76796158|ref|ZP_00778525.1| Iron-containing alcohol dehydrogenase [Thermoanaerobacter ethanolicus...
425.0 [0..2] [462..430]

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Predicted Domain #1
Region A:
Residues: [1-465]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASLARGIL SKMGGSCCPH HAPATNPFKL AKLHGNNKST DYAFEMVCST LRFGKGVTLE  60
   61 IGYDVRNLGA KKTLLITDKN VQNTIAFKNA EQALKMVNIE YEVFDDVLIE PTVNSMQKAI 120
  121 AFAKSKQFDS FIAVGGGSVI DTTKAAALYA SNPEADFLDF VGPPFGKSMQ PKNPMLPLIA 180
  181 VPTTAGTGSE TTAAAIMDLP EHKCKTGIRL RCIKPYLAVV DPLNVMSMPR NVAIYSGFDV 240
  241 LCHALESFTA LPFDQRSPRP ENPGVRPLYQ GSNPISDVWS KEALRIIGKY FRRSIFDPTD 300
  301 EEARTEMLKA SSFAGIGFGN AGVHLCHGLS YPISSQAKSC VADDYPKEKN LIPHGLSVMT 360
  361 TAVADFEFTT AACPDRHLIS AQTLGADIPN NASNEYISRT LCDRLRGYMR DFGVPNGLKG 420
  421 MGFEFSDIEM LTEAASHSVP NIAISPKSAD REIISTLYEK SLTVY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.69897
Match: 1rrmA
Description: Crystal Structure of Lactaldehyde reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydroxyacid-oxoacid transhydrogenase activity 8.51876704052427 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 4.00011629375661 bayes_pls_golite062009
oxidoreductase activity 3.07409531087588 bayes_pls_golite062009
alcohol dehydrogenase activity, metal ion-independent 3.05722501802075 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 2.83823088483915 bayes_pls_golite062009
catalytic activity 2.37357608468991 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2.10085302216488 bayes_pls_golite062009
binding 1.15096180564234 bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity 0.831155115586418 bayes_pls_golite062009
cation binding 0.319000821544479 bayes_pls_golite062009
metal ion binding 0.319000821544479 bayes_pls_golite062009
ion binding 0.313606245452103 bayes_pls_golite062009
protein binding 0.295023706645045 bayes_pls_golite062009
transition metal ion binding 0.259889634539407 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 0.0904828025133766 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle