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Protein Overview: CE24124

General Information:
Name(s) found: CE24124 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00022455 Thymidylate synthase status:Confirmed UniProt:Q9N588 protein_id:CCD66193.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 312 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    dTMP biosynthetic process [IEALink to PubMed article]
    one-carbon metabolic process [IEALink to PubMed article]
    Molecular Function: thymidylate synthase activity [IEALink to PubMed article]
    dihydrofolate reductase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKENIIADA PSDVVKTVQQ QVHLNQDEYK YLKQVEQILR EGTRRDDRTG TGTISIFGMQ  60
   61 SKYCLRNGTI PLLTTKRVYW KGVLEELLWF ISGSTDGKLL MEKNVKIWEK NGDRAFLDNL 120
  121 GFTSREEGDL GPVYGFQWRH FGAKYVDCHT DYSGQGVDQL AEVIRQIKEQ PDSRRIIMSA 180
  181 WNPSDLGQMV LPPCHTMCQF YVDNGELSCQ LYQRSGDMGL GVPFNLASYG LLTHMIAKVC 240
  241 GLKPGTLVHT LGDAHVYSNH VDALKIQLDR EPYAFPKIRF TRDVASIDDF TSDMIALDDY 300
  301 KCHPKIPMDM AV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..312] PSI-BLAST 130.0 Thymidylate synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • thymidylate synthase activity
    		•  6.6988475347328 bayes_pls_golite062009
  • 5,10-methylenetetrahydrofolate-dependent methyltransferase activity
    		•  6.29181090719132 bayes_pls_golite062009
  • binding
    		•  1.89072001556053 bayes_pls_golite062009
  • catalytic activity
    		•  1.73427871128495 bayes_pls_golite062009
  • transferase activity
    		•  1.72626940963556 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.927096828883487 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.91282507161672 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle