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Protein Overview: sod-1

General Information:
Name(s) found: sod-1 / CE23550 [WormBase]
Description(s) found:
Found 20 descriptions.
SHOW ALL
  • WBGene00004930 locus:sod-1 Superoxide dismutase [Cu-Zn] status:Confirmed UniProt:P34697 protein_id:CCD64617.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 180 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA]
    cytosol [IDA]
    Biological Process: copper ion transport [IEALink to PubMed article]
    superoxide metabolic process [IEALink to PubMed article]
    removal of superoxide radicals [IC]
    age-dependent response to oxidative stress [IDALink to PubMed articleLink to PubMed article]
    aging [IEPLink to PubMed article]
    regulation of vulval development [IGILink to PubMed article]
    Molecular Function: copper ion binding [IDALink to PubMed article][IEALink to PubMed article]
    metal ion binding [IEALink to PubMed article]
    copper ion transmembrane transporter activity [IEALink to PubMed article]
    superoxide dismutase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFMNLLTQVS NAIFPQVEAA QKMSNRAVAV LRGETVTGTI WITQKSENDQ AVIEGEIKGL  60
   61 TPGLHGFHVH QYGDSTNGCI SAGPHFNPFG KTHGGPKSEI RHVGDLGNVE AGADGVAKIK 120
  121 LTDTLVTLYG PNTVVGRSMV VHAGQDDLGE GVGDKAEESK KTGNAGARAA CGVIALAAPQ 180
  181

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..180] PSI-BLAST 46.69897 Cu,Zn superoxide dismutase, SOD

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein phosphatase 2B binding
    		•  13.5719110466797 bayes_pls_golite062009
  • superoxide dismutase activity
    		•  12.1093323949609 bayes_pls_golite062009
  • oxidoreductase activity, acting on superoxide radicals as acceptor
    		•  12.1093323949609 bayes_pls_golite062009
  • chaperone binding
    		•  5.11696266714142 bayes_pls_golite062009
  • superoxide dismutase copper chaperone activity
    		•  4.90125496493753 bayes_pls_golite062009
  • copper ion binding
    		•  4.51765925795625 bayes_pls_golite062009
  • protein phosphatase binding
    		•  3.26481550276071 bayes_pls_golite062009
  • phosphatase binding
    		•  3.1414149853516 bayes_pls_golite062009
  • transition metal ion binding
    		•  2.451533032488 bayes_pls_golite062009
  • binding
    		•  2.28211284921339 bayes_pls_golite062009
  • protein binding
    		•  1.96660745768497 bayes_pls_golite062009
  • enzyme binding
    		•  1.82618630359051 bayes_pls_golite062009
  • cation binding
    		•  1.79413011653575 bayes_pls_golite062009
  • metal ion binding
    		•  1.79413011653575 bayes_pls_golite062009
  • ion binding
    		•  1.78699219376941 bayes_pls_golite062009
  • catalytic activity
    		•  1.09233965765942 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  0.658369569046781 bayes_pls_golite062009
  • metallochaperone activity
    		•  0.515959593535099 bayes_pls_golite062009
  • copper chaperone activity
    		•  0.412497194733789 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.32642292951469 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.262312399748454 bayes_pls_golite062009
  • zinc ion binding
    		•  0.25600715352161 bayes_pls_golite062009
  • antioxidant activity
    		•  0.240491838042064 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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