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Protein Overview: CE22127

General Information:
Name(s) found: CE22127 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00012983 locus:men-1 Malic enzyme status:Partially_confirmed UniProt:Q9U296 protein_id:CAB54452.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 620 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: malate metabolic process [IEALink to PubMed article]
    Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [IEALink to PubMed article]
    metal ion binding [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    malic enzyme activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRLSPASI RRLSTSTRCL SDKNEPDLSD PKTLALHKLY RPERTTPQKR GIDLLKSPGL  60
   61 NKGMAFSLHE RQYLGVHGLL PPAFMTEEQQ AYRIITKLRQ QPDNLAKYIQ LDSLQDRNEK 120
  121 LYYRVLCDNV KELMPIVYTP TVGQACQHFG FIYRNPKGLY ITINDNSISK IHQILANWPT 180
  181 ENVRAIVITD GERILGLGDL GTYGIGIPVG KLALYVALAG IRPEWCLPVI LDVGTDNSEL 240
  241 LNDPFYTGLR RKRVRGPEYD TLVDNFMKAA TKRFGRDTLI QFEDFGNQNA YRLLDRYKGE 300
  301 YCMFNDDIQG TAAVVVAGLL ASTRITKKKL SQERIVFLGA GGAATGVAEM CVRQMMDEGL 360
  361 SEEEACGRIY MVDIEGLITT SRSKSLGERH VKFAKDLPDT KNLLEVVKTV KPGALIGAST 420
  421 VAGAFTEDII KEMARLNPRP IIFALSNPTS KAECTAETAY RCTNGAVLFA SGSPFENVEM 480
  481 NGKLYKPGQG NNAYIFPGVA LGAVLFRTKN IPDKLFLLAA RMVAEAVSEK SLNTYSRVYP 540
  541 RLKDIRELSV KIAVEVGEYC YRHDLATLHP KPDDMEMFIR QNLYSVEYDE LINKTYEWPA 600
  601 KDSKHGFPVP VLRRTSMDEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..620] PSI-BLAST 1000.0 Mitochondrial NAD(P)-dependenent malic enzyme


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle