Protein Overview: msh-2

General Information:
Name(s) found:	msh-2 / CE21000 [WormBase]
Description(s) found: Found 20 descriptions. SHOW ALL	WBGene00003418 locus:msh-2 status:Confirmed UniProt:Q9TXR4 protein_id:CCD68358.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	849 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA] MutSalpha complex [IEA] MutSbeta complex [IEA]
Biological Process:	mutagenesis [IMP ] DNA repair [IMP ] maintenance of DNA repeat elements [IMP ] maintenance of fidelity involved in DNA-dependent DNA replication [IEA] DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis [IMP] mismatch repair [IEA][IMP ] reproduction [IMP]
Molecular Function:	ATP binding [IEA] DNA binding [IEA] mismatched DNA binding [IEA] damaged DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGGKDEASD KALLKILKSK SPNTIAIFSR GEYFSVYGDD ATFVATNIFK SDVCVKTFTL  60
   61 STDNSQQMKY ISVNRGQYEK VVRETIVLLR CSVELYSSEQ GEWKMTKRGS PGNTVDFEQE 120
  121 IGVSDQAPIL AIYIHPGDDD NRVTLCAWDA GNVRIVISEY IDTPSFSQTE QCIFGLCPTE 180
  181 YILVNEGSVA PKAKKIASMF TRMEVHNKQQ LKPKSQWSDV IESVHLDYKD EAEKQNENIK 240
  241 ECLQILHSNA ADEYSISEKY SIFNYGTHGN MLIDSCAVEA LELFQLNYNY LEKSNNLTLY 300
  301 NVLNKCKTLP GEKLLRDWLS RPLCQIDHIN ERLDIVEALF ENQTIRQKLR DSILARMPDC 360
  361 SQLARRLMRK CTLQDLNRFY QAATLLETVE MQLIQLSEAE QFAPSINRLL KSEITEILKK 420
  421 VERFQVLCDE FFDFDYEKEN KEIRVRVDFV PEIQEISEKL EQMERVAEKL RKKYSAKFEC 480
  481 DNLKLDKNSQ YGFYFRVTLK EEKSIRKKDV HILETTKGSG VKFSVGELSD INDEFLEFHL 540
  541 KYTRAEEEVI SMLCKKAEEF IPLIPAMAQL IATLDVFVSL STFAATSSGI YTRPNLLPLG 600
  601 SKRLELKQCR HPVIEGNSEK PFIPNDVVLD KCRLIILTGA NMGGKSTYLR SAALSILLAQ 660
  661 IGSFVPCSSA TISVVDGIFT RVGASDKQSQ GISTFMAEML DCSAILQRAT KNSFVVIDEL 720
  721 GRGTSTFDGF GIASAIAQDI LNRIQCLSIF ATHFHEMGKL AEQPGAVALQ MGVQIENNEI 780
  781 HMLYKVFEGV AQCSFGLQVA KMVGIDENVI NKAAQLLEGL EKKLVIDSKK KKELLESADI 840
  841 RQAILSLVK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.83

Protein Overview: msh-2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: