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Protein Overview: fbf-1

General Information:
Name(s) found: fbf-1 / CE20960 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00001401 locus:fbf-1 Fem-3 mRNA-binding factor 1 status:Confirmed UniProt:Q9N5M6 protein_id:CCD69857.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 614 amino acids

    Gene Ontology:
    Cellular Component: germ cell nucleus [IDALink to PubMed article]
    perinuclear region of cytoplasm [IDALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    feminization of hermaphroditic germ-line [IMPLink to PubMed article]
    germline cell cycle switching, mitotic to meiotic cell cycle [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    masculinization of hermaphrodite soma [IMPLink to PubMed article]
    negative regulation of translation [IGILink to PubMed article]
    masculinization of hermaphroditic germ-line [IMPLink to PubMed article]
    Molecular Function: RNA binding [IEALink to PubMed article]
    mRNA 3'-UTR binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQSKMRYTN QFRKTPQKPT STEVGNHHTP AHSPMAQHET SMWNFNSLNP YFSMLNMNDG  60
   61 MNYARHQQNH IVTSRPPTPL TDLMSLRSFQ SFPNVFMPVS RSRTSSFIQS DTDSSRLEPD 120
  121 DFSQNVRYCS TEIDRNNSSS KNDHLKYSRP ALSRNSRSFT RSNNVLPTWS LDSNGEMRSR 180
  181 LSLSEVLDSG DLMKFAVDKT GCQFLEKAVK GSLTSYQKFQ LFEQVIGRKD DFLKLSTNIF 240
  241 GNYFVQEIIG MSLTTYDDDN IKRQEKLKNF ISSQMTDMCL DKFACRVIQS SLQNMDLSLA 300
  301 CKLVQALPRD ARLIAICVDQ NANHVIQKVV AVIPLKNWEF IVDFVATPEH LRQICFDKYG 360
  361 CRVVQTIIEK LTADSINVDL TSAAQHLRER ALQRLMTSVT NRCQELATNE YANYIIQHIV 420
  421 SNDDLAVYRE CIIEKCLMRN LLSLSQEKFA SHVVEKAFLH APMELLAEMM DEIFDGYMPH 480
  481 PGTGKDALDI MMFHQFGNYV VQCMLTICCD AVSGRRQTKE GSYDHANSFQ VWLKKLHSRV 540
  541 TKERHRLSRF SSGKKMIETL AHLRSTHPIY GLQSSGHESF KTDCFSTASE HDGLELEKNG 600
  601 IEEGNLRLMR TFSP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] MSA 21.302997 View MSA. No confident structure predictions are available.
    2 View Details [167..614] PSI-BLAST 98.522879 Pumilio 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.72717267135753 bayes_pls_golite062009
  • protein binding
    		•  1.01840651819417 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.726577126409925 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.198921736439162 bayes_pls_golite062009
  • translation regulator activity
    		•  0.1178495560226 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.10960901634151 bayes_pls_golite062009
  • catalytic activity
    		•  0.0114279309788371 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle