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Protein Overview: thk-1

General Information:
Name(s) found: thk-1 / CE19154 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00006568 locus:thk-1 Thymidine kinase status:Confirmed UniProt:G5EEZ5 protein_id:CAA19501.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 269 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    thymidine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIEAAKNEM TCCSSNSSLS DFNTLPRCPN RVGSITVILG PMFSGKTTEL LRLHDRQIIA  60
   61 KRTCVLVKYA GDTRYDADLV ATHSKMTGQG RTVKAHRLSE VQSQIFNDEV QVVSIDEGQF 120
  121 FEDLAETCEE LAQRGKVVCV AALNGTFERK PFPQISLLLP YANEIKQVTA VCVECGSQAN 180
  181 FSFRSTLDKK VEVIGGSDTY TALCRECYVQ KSEEKDAEEQ MKTGCDKNEN DITGIFLAKK 240
  241 EQRSDGSVSP PRKKIGLSKS MALEATART

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..269] PSI-BLAST 73.30103 No description for 2orvA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.66392587433723 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  2.24094813695083 bayes_pls_golite062009
  • kinase activity
    		•  2.0779386406753 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  1.96697952975573 bayes_pls_golite062009
  • binding
    		•  1.88744046151476 bayes_pls_golite062009
  • protein binding
    		•  1.41749048987708 bayes_pls_golite062009
  • DNA binding
    		•  1.22619720972604 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.17199530230795 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16376707327858 bayes_pls_golite062009
  • transcription factor activity
    		•  0.472763834470731 bayes_pls_golite062009
  • adenylate kinase activity
    		•  0.447752711852745 bayes_pls_golite062009
  • catalytic activity
    		•  0.101795606736461 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle