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Protein Overview: nkat-1

General Information:
Name(s) found: nkat-1 / CE18648 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00009232 locus:nkat-1 status:Partially_confirmed UniProt:Q9XX97 protein_id:CAA20930.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 437 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: aromatic amino acid family metabolic process [IEALink to PubMed article]
    cellular amino acid and derivative metabolic process [IEALink to PubMed article]
    biosynthetic process [IEALink to PubMed article]
    histidine biosynthetic process [IEALink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEALink to PubMed article]
    transferase activity, transferring nitrogenous groups [IEALink to PubMed article]
    L-tyrosine:2-oxoglutarate aminotransferase activity [IEALink to PubMed article]
    transaminase activity [IEALink to PubMed article]
    histidinol-phosphate transaminase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTNFARQPS ENVGEHQESI WVEFGKLAIE NKAVSLGQGF PDSPAPKFVT EILKDIASHP  60
   61 EKIESHQYTR AFGHPDLVGI LSKIYSYFYG VNVNATDDIL ITVGAYNALY YSFLGWISKG 120
  121 DEVIIIEPAF DCYFPQVKFA GGTPISVVMK LKEGSKSASQ FTIDFEELEK KINKRTKMIV 180
  181 INNPHNPTGK LFSREELQHI AELARNYDLI VVADEVYEFH VSQPKEMIRF ASLPGMYERT 240
  241 ISIGSAGKAL SVTGWKLGWA IGPQHLLSPL KTISQNCVYT CPTPIQLAIA RAFQQDWPKF 300
  301 MENPNQSYLA TGLPKEVMQK RKILANMLEK ANFQTILPEA GFFMLAECKL PMKSFSFSPI 360
  361 VGKDPLDVQY SKWLCREKKL AVIPFSIFFS SKDQKHLSGR FVRLCFFKKD TTLQAAEKIF 420
  421 KTFENNDEKI LERPVKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..437] PSI-BLAST 90.69897 Crystal structure of human kynurenine aminotransferase I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  5.51961002550688 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.63055151623667 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.63055151623667 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • 4-aminobutyrate transaminase activity
    		•  0.99097016439114 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  0.54326874956263 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.319452731970428 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • aromatic-amino-acid:2-oxoglutarate aminotransferase activity
    		•  0.0916183433120769 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.0833010353195099 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.013097682076602 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle