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View Structure Prediction Details

Protein: nkat-1
Organism: Caenorhabditis elegans
Length: 437 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nkat-1.

Description E-value Query
Range
Subject
Range
gi|166857245, gi... - gi|76795487|ref|ZP_00777860.1| Aminotransferase, class I and II [Thermoanaerobacter ethanolicus ATCC...
gi|241902537, gi... - gi|241902537|ref|ZP_04787270.1| aminotransferase class I and II [Thermoanaerobacter brockii subsp. f...
354.0 [0..3] [427..1]

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Predicted Domain #1
Region A:
Residues: [1-437]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTNFARQPS ENVGEHQESI WVEFGKLAIE NKAVSLGQGF PDSPAPKFVT EILKDIASHP  60
   61 EKIESHQYTR AFGHPDLVGI LSKIYSYFYG VNVNATDDIL ITVGAYNALY YSFLGWISKG 120
  121 DEVIIIEPAF DCYFPQVKFA GGTPISVVMK LKEGSKSASQ FTIDFEELEK KINKRTKMIV 180
  181 INNPHNPTGK LFSREELQHI AELARNYDLI VVADEVYEFH VSQPKEMIRF ASLPGMYERT 240
  241 ISIGSAGKAL SVTGWKLGWA IGPQHLLSPL KTISQNCVYT CPTPIQLAIA RAFQQDWPKF 300
  301 MENPNQSYLA TGLPKEVMQK RKILANMLEK ANFQTILPEA GFFMLAECKL PMKSFSFSPI 360
  361 VGKDPLDVQY SKWLCREKKL AVIPFSIFFS SKDQKHLSGR FVRLCFFKKD TTLQAAEKIF 420
  421 KTFENNDEKI LERPVKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.69897
Match: 1w7lA
Description: Crystal structure of human kynurenine aminotransferase I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
L-aspartate:2-oxoglutarate aminotransferase activity 5.51961002550688 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 1.63055151623667 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 1.63055151623667 bayes_pls_golite062009
transferase activity 1.44093490824786 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
4-aminobutyrate transaminase activity 0.99097016439114 bayes_pls_golite062009
5-aminolevulinate synthase activity 0.54326874956263 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.319452731970428 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009
aromatic-amino-acid:2-oxoglutarate aminotransferase activity 0.0916183433120769 bayes_pls_golite062009
cystathionine beta-lyase activity 0.0833010353195099 bayes_pls_golite062009
nucleic acid binding 0.013097682076602 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle