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Protein Overview: prmt-3

General Information:
Name(s) found: prmt-3 / CE18281 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00011939 locus:prmt-3 status:Confirmed UniProt:O02325 protein_id:CAB07676.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 680 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: rRNA modification [IEALink to PubMed article]
    Molecular Function: rRNA methyltransferase activity [IEALink to PubMed article]
    rRNA (adenine-N6,N6-)-dimethyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPAQETPC FSMEKAERAF LDGNFEEALK HFFVCIRMLP VERRGVYEDQ FAAALHGWIA  60
   61 LDHNNASRAV CLYPQIKELF PETIRTKIAL IRAVQGTEQS KWLLNCLPIC KDSMDLATKP 120
  121 EDLVALRIAR VNLTTIPFPQ WHIRMINDVK RNEAFAKALN DTIKSRITVV FDIGSGTGIL 180
  181 SAIAARKTNL VTALEENMCL TMISKEVLKR NGVESRVNVH AKNSTYFETC EKADIVVSET 240
  241 LDCCVFGEKI VETFLDAHVR FSHDRTIFIP HQATVYVRLF SCREIFDIHC QDYGGVRYRS 300
  301 EYVKIGESDA EQPYWCASAA DYSQFELLSG SVAMHSVDFS SIANLKDSLA NSNSFKIRPA 360
  361 KDGVAHGFSV HFTSDLTGHG DNIIDSSKSR AWDLGIIPFK EPCLVKCDKE YEGSWKLLNN 420
  421 RLDVYNDFYD ENLQKHEDSL RYETASLDQL QKIRDDSYFK AMMGEIDPIE LPFTRDISSS 480
  481 IPAQCVLNTV ESQTPIRHLI TNFCRYDGTL DQETFFRIEE FVGFRDHVQK IVPTKFRILG 540
  541 HLFYSDRVHF DARPDPSAHC QVDLSTVRSF NLREMRDIRL TQREDIVMAS KEFVLYDFNI 600
  601 SAEKFRQDTY ITVTQDVTVQ PTRPIADGVI YEFEILGIRN TKLRPVAAFL FPERVNTNPD 660
  661 MTVVFDLHLG EMLISLKDLP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] PSI-BLAST 14.69897 Crystal Structure of RumA, the iron-sulfur cluster containing E. coli 23S Ribosomal RNA 5-Methyluridine Methyltransferase
    2 View Details [136..453] PSI-BLAST 69.221849 Structure of the Predominant protein arginine methyltransferase PRMT1
    3 View Details [454..556] MSA 1.073987 View MSA. No confident structure predictions are available.
    4 View Details [557..680] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.723277178398499 bayes_pls_golite062009
  • transferase activity
    		•  0.64512166557639 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.54403439349476 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.54389223881989 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle