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View Structure Prediction Details

Protein: prmt-3
Organism: Caenorhabditis elegans
Length: 680 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prmt-3.

Description E-value Query
Range
Subject
Range
gi|187036701, gi... - gi|39585791|emb|CAE59993.1| Hypothetical protein CBG03486 [Caenorhabditis briggsae], gi|187036701|em...
gi|157757069 - gi|157757069|ref|XP_001670878.1| Hypothetical protein CBG03486 [Caenorhabditis briggsae AF16]
547.0 [0..11] [678..12]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPAQETPC FSMEKAERAF LDGNFEEALK HFFVCIRMLP VERRGVYEDQ FAAALHGWIA  60
   61 LDHNNASRAV CLYPQIKELF PETIRTKIAL IRAVQGTEQS KWLLNCLPIC KDSMDLATKP 120
  121 EDLVALRIAR VNLTT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.69897
Match: 1uwvA
Description: Crystal Structure of RumA, the iron-sulfur cluster containing E. coli 23S Ribosomal RNA 5-Methyluridine Methyltransferase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [136-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPFPQWHIRM INDVKRNEAF AKALNDTIKS RITVVFDIGS GTGILSAIAA RKTNLVTALE  60
   61 ENMCLTMISK EVLKRNGVES RVNVHAKNST YFETCEKADI VVSETLDCCV FGEKIVETFL 120
  121 DAHVRFSHDR TIFIPHQATV YVRLFSCREI FDIHCQDYGG VRYRSEYVKI GESDAEQPYW 180
  181 CASAADYSQF ELLSGSVAMH SVDFSSIANL KDSLANSNSF KIRPAKDGVA HGFSVHFTSD 240
  241 LTGHGDNIID SSKSRAWDLG IIPFKEPCLV KCDKEYEGSW KLLNNRLDVY NDFYDENLQK 300
  301 HEDSLRYETA SLDQLQKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.221849
Match: 1or8A
Description: Structure of the Predominant protein arginine methyltransferase PRMT1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.723277178398499 bayes_pls_golite062009
transferase activity 0.64512166557639 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.54403439349476 bayes_pls_golite062009
methyltransferase activity 0.54389223881989 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [454-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDDSYFKAMM GEIDPIELPF TRDISSSIPA QCVLNTVESQ TPIRHLITNF CRYDGTLDQE  60
   61 TFFRIEEFVG FRDHVQKIVP TKFRILGHLF YSDRVHFDAR PDP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [557-680]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAHCQVDLST VRSFNLREMR DIRLTQREDI VMASKEFVLY DFNISAEKFR QDTYITVTQD  60
   61 VTVQPTRPIA DGVIYEFEIL GIRNTKLRPV AAFLFPERVN TNPDMTVVFD LHLGEMLISL 120
  121 KDLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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