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Protein Overview: CE18020

General Information:
Name(s) found: CE18020 [WormBase]
Description(s) found:
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  • WBGene00019492 status:Confirmed UniProt:Q21284 protein_id:CCD62516.1 [WormBase]
  • gi|3805682|gb|AAC69104.1| Hypothetical protein K07E3.4a [Caenorhabditis elegans] [NCBI NR]
  • pir||F89582 protein K07E3.4b [imported] - Caenorhabditis elegans [NCBI NR]
  • gi|17568739|ref|NP_509360.1| hypothetical protein K07E3.4 [Caenorhabditis elegans] [NCBI NR]
  • gi|17568737|ref|NP_509361.1| hypothetical protein K07E3.4 [Caenorhabditis elegans] [NCBI NR]
  • gi|15789308|gb|AAC69101.2| Hypothetical protein K07E3.4b [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE18020 WBGene00019492 status:Confirmed TR:Q21284 protein_id:AAC69101.2 [wormpep150.fasta]
  • CE18020 WBGene00019492 tetrahydrofolate synthase status:Confirmed TR:Q21284 protein_id:AAC69104.1 [wormpep150.fasta]
  • 18020 WBGene00019492 status:Confirmed TR:Q21284 protein_id:AAC69101.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • 18020 WBGene00019492 tetrahydrofolate synthase status:Confirmed TR:Q21284 protein_id:AAC69104.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • methylenetetrahydrofolate dehydrogenase (XI700) [Caenorhabditis elegans]gi|17568739|ref|NP_509360.1| methylenetetrahydrofolate dehydrogenase (69.0 kD) (XI700) [Caenorhabditis elegans]gi|15789308|gb|AAC69101.2| Hypothetical protein K07E3.4b [Caenorhabdit [nrdb_11152004_Chlamydomonas]
  • status:Confirmed TR:Q21284 protein_id:AAC69101.2 [wormpep115.fasta.reversed]
  • CE18020 tetrahydrofolate synthase status:Confirmed TR:Q21284 protein_id:AAC69104.1 [wormpep80.hongbin]
  • CE18020 status:Confirmed TR:Q21284 protein_id:AAC69101.2 [wormpep80.hongbin]
  • CE18020 WBGene00019492 tetrahydrofolate synthase status:Confirmed UniProt:Q21284_CAEEL protein_id:AAC69104.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE18020 WBGene00019492 status:Confirmed UniProt:Q21284_CAEEL protein_id:AAC69101.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE18020 WBGene00019492 tetrahydrofolate synthase status:Confirmed UniProt:Q21284_CAEEL protein_id:AAC69104.1| [wormORF-contam.fasta]
  • CE18020 WBGene00019492 status:Confirmed UniProt:Q21284_CAEEL protein_id:AAC69101.2| [wormORF-contam.fasta]
  • Hypothetical protein K07E3.4b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • K07E3.4a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • K07E3.4b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein K07E3.4a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE18020 WBGene00019492 status:Confirmed UniProt:Q21284 protein_id:AAC69101.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE18020 WBGene00019492 tetrahydrofolate synthase status:Confirmed UniProt:Q21284 protein_id:AAC69104.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE18020 WBGene00019492 tetrahydrofolate synthase status:Confirmed UniProt:Q21284 protein_id:CCD62515.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE18020 WBGene00019492 status:Confirmed UniProt:Q21284 protein_id:CCD62516.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE18020 WBGene00019492 status:Confirmed UniProt:Q21284 protein_id:CCD62515.1 [wormpep246-ecoli-contam.fasta]
  • Uncharacterized protein OS=Caenorhabditis elegans GN=CELE_K07E3.4 PE=1 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 640 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: folic acid and derivative biosynthetic process [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    formate-tetrahydrofolate ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTWNVEYLK PTLLTPVPSD IAISRAQPPK DIEKVAGEIG IKQEELDLYG RKKAKVSLDI  60
   61 LDRLSEVKNG KYVVVAGITP TPLGEGKSTT TIGLVQALGA HLHKKVFACV RQPSQGPTFG 120
  121 IKGGAAGGGY SQVIPMEEFN LHLTGDIHAI TAANNLLAAA IDARMFHEST QATDALFNRL 180
  181 APKNKKGVRP LSEIQLRRLD RLGIPRVDDA ENLSEEQRVS FARLNIDPAT ITWNRVMDTN 240
  241 DRFLRKIEIG MGPNEKGHTR TTQFDITVAS ELMAILALTT SLADMQERIA RIVIGSDKAG 300
  301 NPVTADDIGV TGALTVLMRD TVRPNLMQTL EGTPVFVHAG PFANIAHGQS SILADKVALK 360
  361 LAGPDGFVIT EAGFGADIGM EKFFNIKCRY SGLQPSAVVL VATVRALKMH GGGPSVVAGA 420
  421 PLKHEYLDEN IPLVEGGCDS NLRKQIENAN KFGIPVVVCV NKFATDTDKE LELVCSKAKE 480
  481 YGAFDAVVSE HWSQGGAGAV ALANSLVNAT TGHPKQFKFL YNLDLSLEDK IATIAKEIYG 540
  541 ADGIELSDEA KQKLERYTRQ GFSKLPICMA KTHLSLSSDP TKKGAPTGFT LPIRDVRASV 600
  601 GAGFIYPLVG EMTTMPGLNT RPCFYDITID PVTEIIDGLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..640] PSI-BLAST 1000.0 Formyltetrahydrofolate synthetase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.51683451033161 bayes_pls_golite062009
  • DNA binding
    		•  2.12258000781149 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09345198747025 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • transcription factor activity
    		•  0.887108427603557 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  0.12351419478929 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • helicase activity
    		•  0.0775311459068899 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle