YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: cha-1

General Information:
Name(s) found: cha-1 / CE17308 [WormBase]
Description(s) found:
Found 26 descriptions.
SHOW ALL
  • WBGene00000481 locus:cha-1 Choline O-acetyltransferase status:Confirmed UniProt:P32756 protein_id:CCD68242.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 627 amino acids

    Gene Ontology:
    Cellular Component: synapse [IDALink to PubMed article]
    neuron projection [IDALink to PubMed article]
    Biological Process: acetylcholine biosynthetic process [IMP]
    Molecular Function: acyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKEKVDELP PNDNWYETAL PKPPVPSLEA TLDRYLEYAA VVAVGQKASL ATTHDAAHKF  60
   61 VRQATPLQEQ LLEIAEKSPN WATKFWLPEM YMRVRMPTPV NSNPGYIFPK VKFETKEDHI 120
  121 KYTALLTRGL LEYKNLIDTK QVCREKSTGA QKLQMCMEQY DRVLSCYREP GVGEDTQIRK 180
  181 QKTNDGNEHV LVMCRNQTFL LHSRINGALV SYADVEYQLA QIEEISKINQ NNTANIGASG 240
  241 VGPRDNAALF WQDMLTVEQN SKSYEWVKSA LFVVCLDMED PIDYGKNDTM SISEKEKEFV 300
  301 ARGYSTLTGH GSSKFGLNRW YDATIQLVVS SSGVNGLCIE HSTAEGIVII NMAETAIRYA 360
  361 QKYFKSKMVW NDVRNVHPKS LTWHFSENSR NILKKQAEVF DELANELELE VLIFNEFGKD 420
  421 SIKNWRVSPD GFIQLIMQLA HYKTHGHLVS TYESASVRRF GAGRVDNIRA NTQEALEWVT 480
  481 AMASKKESKE RKLELFKKAV LKQVKVTLEN ISGYGVDNHL CALFCLARER EETTGEDIPS 540
  541 LFLDPLWSEV MRFPLSTSQV TTSLDIPDCY LTYGAVVRDG YGCPYNIQPD RVIFAPTAFR 600
  601 SDPRTDLQHF KKSLAGAMRD VKELLSN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..627] PSI-BLAST 1000.0 Structural Insights and Functional Implications of Choline Acetyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • carnitine O-acyltransferase activity
    		•  7.54616819269984 bayes_pls_golite062009
  • carnitine O-acetyltransferase activity
    		•  7.38318207912192 bayes_pls_golite062009
  • choline O-acetyltransferase activity
    		•  6.09272417016149 bayes_pls_golite062009
  • octanoyltransferase activity
    		•  4.52268776339565 bayes_pls_golite062009
  • O-octanoyltransferase activity
    		•  4.52268776339565 bayes_pls_golite062009
  • carnitine O-octanoyltransferase activity
    		•  4.52268776339565 bayes_pls_golite062009
  • S-acyltransferase activity
    		•  4.44987112475286 bayes_pls_golite062009
  • carnitine O-palmitoyltransferase activity
    		•  3.83467723502092 bayes_pls_golite062009
  • O-palmitoyltransferase activity
    		•  3.83467723502092 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.7327637835604 bayes_pls_golite062009
  • O-acyltransferase activity
    		•  3.7101056995294 bayes_pls_golite062009
  • dihydrolipoamide S-acyltransferase activity
    		•  3.56004160262054 bayes_pls_golite062009
  • dihydrolipoyllysine-residue acetyltransferase activity
    		•  3.36143851730669 bayes_pls_golite062009
  • S-acetyltransferase activity
    		•  3.32990830846882 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.08588280042054 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.027770031317 bayes_pls_golite062009
  • S-succinyltransferase activity
    		•  3.02354522717247 bayes_pls_golite062009
  • dihydrolipoyllysine-residue succinyltransferase activity
    		•  3.02354522717247 bayes_pls_golite062009
  • O-acetyltransferase activity
    		•  2.37098434941789 bayes_pls_golite062009
  • palmitoyltransferase activity
    		•  2.23754077046213 bayes_pls_golite062009
  • succinyltransferase activity
    		•  2.08404693277798 bayes_pls_golite062009
  • choline binding
    		•  1.59193088660278 bayes_pls_golite062009
  • catalytic activity
    		•  1.51562638409295 bayes_pls_golite062009
  • acetyltransferase activity
    		•  1.12787027896966 bayes_pls_golite062009
  • transferase activity
    		•  1.08341671157927 bayes_pls_golite062009
  • binding
    		•  0.999555841397607 bayes_pls_golite062009
  • pyruvate dehydrogenase activity
    		•  0.85838145786229 bayes_pls_golite062009
  • protein binding
    		•  0.104367069798378 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle