Protein Overview: unc-17

General Information:
Name(s) found:	unc-17 / CE17307 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006756 locus:unc-17 Vesicular acetylcholine transporter unc-17 status:Confirmed UniProt:P34711 protein_id:CCD68241.1 [WormBase] gi\|71999703\|ref\|NP_001023602.1\| UNCoordinated family member (unc-17) [Caenorhabditis elegans] [NCBI NR] gi\|501062\|gb\|AAC13764.1\| UNC-17 [Caenorhabditis elegans] [NCBI NR] gi\|464998\|sp\|P34711.1\|UNC17_CAEEL RecName: Full=Vesicular acetylcholine transporter unc-17; AltName: Full=Uncoordinated protein 17 [NCBI NR] gi\|385199\|gb\|AAC14456.1\| acetylcholine transporter [Caenorhabditis elegans] [NCBI NR] gi\|2662614\|gb\|AAB88371.1\| Uncoordinated protein 17, isoform a [Caenorhabditis elegans] [NCBI NR] ref\|NP_500386.2\| acetylcholine transporter, abnormal CHoline Acetyltransferase CHA-1, UNCoordinated locomotion UNC-17 (58.6 kD) (unc-17+cha-1) [Caenorhabditis elegans] [NCBI NR] pir\|\|S53603 acetylcholine transport protein unc-17, vesicular - Caenorhabditis elegans [NCBI NR] Vesicular acetylcholine transporter unc-17 OS=Caenorhabditis elegans GN=unc-17 PE=1 SV=1 [Swiss-Prot] (P34711) Vesicular acetylcholine transporter unc-17 (Uncoordinated protein 17) [Swiss-Prot] [wormpep67.fasta] CE17307 WBGene00006756 locus:unc-17 putative acetylcholine transporter status:Confirmed [wormpep150.fasta] 17307 WBGene00000481 locus:cha-1 putative acetylcholine transporter status:Confirmed SW:P34711 protein_id:AAB88371.1 [wormpep130-phg-ecoli-orf-rand.fasta] acetylcholine transporter, abnormal CHoline Acetyltransferase CHA-1, UNCoordinated locomotion UNC-17 (58.6 kD) (unc-17+cha-1) [Caenorhabditis elegans]gi\|2662614\|gb\|AAB88371.1\| Uncoordinated protein 17, isoform a [Caenorhabditis elegans]gi\|385199\|gb\|AAC1 [nrdb_11152004_Chlamydomonas] CE17307 WBGene00006756 locus:unc-17 putative acetylcholine transporter status:Partially_confirmed SW:P34711 protein_id:AAB88371.1 [wormpep132.fasta] 17307 WBGene00006756 locus:unc-17 putative acetylcholine transporter status:Confirmed [wormpep150-phg-orf-ecoli-rand.fasta] locus:unc-17 putative acetylcholine transporter status:Confirmed SW:P34711 protein_id:AAB88371.1 [wormpep115.fasta.reversed] CE17307 locus:unc-17 putative acetylcholine transporter status:Confirmed SW:P34711 protein_id:AAB88371.1 [wormpep80.hongbin] CE17307 WBGene00006756 locus:unc-17 putative acetylcholine transporter status:Confirmed [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE17307 WBGene00006756 locus:unc-17 putative acetylcholine transporter status:Confirmed\| [wormORF-contam.fasta] Vesicular acetylcholine transporter unc-17 (Uncoordinated protein 17) [nr-271106-contam.fasta] UNC-17 [nr-271106-contam.fasta] Uncoordinated protein 17, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta] UNCoordinated family member (unc-17) [Caenorhabditis elegans] [nr-271106-contam.fasta] acetylcholine transporter [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE17307 WBGene00006756 locus:unc-17 putative acetylcholine transporter status:Confirmed UniProt:P34711 protein_id:CCD68241.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE17307 WBGene00006756 locus:unc-17 status:Confirmed UniProt:P34711 protein_id:CCD68241.1 Vesicular acetylcholine transporter unc-17 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	532 amino acids
Gene Ontology:
Cellular Component:	synaptic vesicle [IDA] integral to membrane [IEA] integral to synaptic vesicle membrane [NAS] synapse [IDA ] neuron projection [IDA]
Biological Process:	regulation of neurotransmitter secretion [IMP] regulation of pharyngeal pumping [IGI][IMP] drug transport [IEA] acetylcholine transport [ISS] regulation of locomotion [IMP] phosphate transport [IEA] nematode larval development [IMP] transport [IEA]
Molecular Function:	phosphate transmembrane transporter activity [IEA] acetylcholine transmembrane transporter activity [ISS] drug transmembrane transporter activity [IEA] transporter activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFNVPVINR DSEILKADAK KWLEQQDNQK KCVLVIVSIA LLLDNMLYMV IVPIIPKYLR  60
   61 DIHNYQVTFE GYHNETSQLA NGTYLVREVG GRINFLDEEL ELGWLFASKA LLQIFVNPFS 120
  121 GYIIDRVGYE IPMILGLCTM FFSTAIFALG KSYGVLLFAR SLQGFGSAFA DTSGLAMIAD 180
  181 RFTEENERSA ALGIALAFIS FGCLVAPPFG SVLYSLAGKP VPFLILSFVC LADAIAVFMV 240
  241 INPHRRGTDS HGEKVQGTPM WRLFMDPFIA CCSGALIMAN VSLAFLEPTI TTWMSEMMPD 300
  301 TPGWLVGVIW LPPFFPHVLG VYVTVKMLRA FPHHTWAIAM VGLAMEGIAC FAIPYTTSVM 360
  361 QLVIPLSFVC FGIALIDTSL LPMLGHLVDT RHVSVYGSVY AIADISYSLA YAFGPIIAGW 420
  421 IVTNWGFTAL NIIIFATNVT YAPVLFLLRK VHSYDTLGAK GDTAEMTQLN SSAPAGGYNG 480
  481 KPEATTAESY QGWEDQQSYQ NQAQIPNHAV SFQDSRPQAE FPAGYDPLNP QW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..532]	PSI-BLAST	38.69897	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

Protein Overview: unc-17

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: