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Protein Overview: prp-21

General Information:
Name(s) found: prp-21 / CE17296 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00004188 locus:prp-21 status:Confirmed UniProt:G5ECL3 protein_id:CCD73645.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 655 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: collagen and cuticulin-based cuticle attachment to epithelium [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed articleLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    protein modification process [IEALink to PubMed article]
    RNA processing [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAVVSNREE DSMNNEPSLS GRAIIGLIYP PPDIRTIVDK TARFAAKNGV DFENKIREKE  60
   61 AKNPKFNFLS ITDPYHAYYK KMVYDFSEGR VEAPKVPQAV KEHVKKAEFV PSAPPPAYEF 120
  121 SADPSTINAY DLDLIRLVAL FVARNGRQFL TQLMTREARN YQFDFLKPAH CNFTYFTKLV 180
  181 DQYQKVLVPS TNVVAQLQDD ATNKKRLIED INYRVSWEKH QKGLKDREEA EAEKERQAYA 240
  241 SIDWHDFVVV QTVDFQPGDT SQLPPLCTPK DVGARILLEA RNEMQKAAAE MQEMDMEESD 300
  301 SDDEDAVQAP EAPAFTAPLP PTKQKDVIVR DYDPKRNVTQ KPKAVENWII SPLTGERIPS 360
  361 DKLAEHVRYN TVDSQYKEDR DRHIGERSTE EPVLALGADI SRNLGNFAER RTDIFGVGGE 420
  421 QTMIGKKLGE EDNSQQGQNK LIWDGTEETR DMITRAVQNK VTLDQQINEI HRQHGFVADP 480
  481 SKEKIGAQQV PRHQSTQGNV TITQGITNIP GQMPSGWPPV PPMGMPGMPN QALPPIRQMD 540
  541 FGGGPPAKRP RTEDDLIPEA DWLKKVNGAI SLNVHLPQAP EHGMDGSIVQ FTIQVTAPMS 600
  601 ELKQQIQDRY GMPVGKQKLM SDGLFVKDNM SSAFYNLADR TAIYLQVKER GGKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..110] PSI-BLAST 21.39794 No description for 2dt6A was found.
    2 View Details [111..201] PSI-BLAST 24.221849 No description for 2dt7B was found.
    3 View Details [202..410] MSA 1.059966 View MSA. No confident structure predictions are available.
    4 View Details [411..530] MSA 1.037979 View MSA. No confident structure predictions are available.
    5 View Details [531..655] PSI-BLAST 26.522879 Solution structure of Ubiquitin-like domain in SF3a120

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • RNA binding
    		•  2.5865157751042 bayes_pls_golite062009
  • binding
    		•  2.19381585790185 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.967509006593 bayes_pls_golite062009
  • protein binding
    		•  1.89134588490127 bayes_pls_golite062009
  • structural molecule activity
    		•  1.52853261170163 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.11533445164506 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.896431097217265 bayes_pls_golite062009
  • DNA binding
    		•  0.859811565165317 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle