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Protein Overview: nph-1

General Information:
Name(s) found: nph-1 / CE16278 [WormBase]
Description(s) found:
Found 24 descriptions.
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  • WBGene00010898 locus:nphp-1 Nephrocystin-1-like protein status:Partially_confirmed UniProt:O17972 protein_id:CAA90133.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 682 amino acids

    Gene Ontology:
    Cellular Component: microtubule basal body [IDA]
    nonmotile primary cilium [IDA]
    Biological Process: vulval location [IMP]
    turning behavior involved in mating [IMP]
    response to hermaphrodite contact [IMP]
    sensory cilium assembly [IMP]
    protein localization [IGI]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIFGSILSL QDAINRFPQF EYQINRLEKE QKDTEAASRA SFRKHFVRQC QELHRQLDDH  60
   61 RNRIEKAKTD ETYKKENALE QLDKLKQRLT ALSPEKEQLS FSVSVDSQSE EEKPKMAAIG 120
  121 RRKSTMYNDD ESEDSDNDSE IIETDVQLDD PLPSQPQPPQ QQHQQPQPKP RQPITITKPL 180
  181 ESKTLNERQE LDEVISRLQN PSRGDSGEVM EPVVVRGNVF VAIDSWDAEA EGDLELIKGK 240
  241 KYRITQTRSD GWWTALDEYG QRGLVPKTYL QHVKEKPKNV PSKVSSRLGV RDSVIGISTT 300
  301 TDPSRREANR QASRVDDCLG KAYDNDTHLS LVCHMAPRLS TSNIGFHDLF WSHYKDQVYK 360
  361 RTVHISKIIR LVRFEKMPLI EHKALVRMAL VDITNPKSTQ IVSNVHTLVP RVKSSTWYFE 420
  421 KKESQTRSCI EFSDFVLRSN YRSPTVVLVV EASHLVKTQI GIEEKSLGHT YLRLIIDDKA 480
  481 VPSRTNVLYL DDEVMTKMKL PEASKRRVLV QVMDVPKDKV SYVDSLPDVI VFNALYLPFF 540
  541 HFYRRRAGTI LIRDNRNPLS AEFISDPLLS VFPFVCDQHD IMDIMLKIWK TKKKVLAKKN 600
  601 EAEQTAEFFQ TFLHTAFFIH GIRMISYDVK DDLTLSIRQQ TMQRFVDALN KGLFKQFIAD 660
  661 QQCKPINIID YSLDLLGNHS ID

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] PSI-BLAST 17.522879 Crystal structure of endophilin-A1 BAR domain
    2 View Details [130..456] PSI-BLAST 42.522879 No description for 2h8hA was found.
    3 View Details [457..533] PSI-BLAST 8.69897 Phosphoinositide-specific phospholipase C, isozyme D1 (PLC-D!); PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain; Phospholipase C isozyme D1 (PLC-D1)
    4 View Details [534..682] MSA 1.013943 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle