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View Structure Prediction Details

Protein: nph-1
Organism: Caenorhabditis elegans
Length: 682 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nph-1.

Description E-value Query
Range
Subject
Range
gi|57098287 - gi|57098287|ref|XP_532954.1| PREDICTED: similar to Nephrocystin-1 (Juvenile nephronophthisis 1 prote...
562.0 [0..36] [677..3]

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Predicted Domain #1
Region A:
Residues: [1-129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIFGSILSL QDAINRFPQF EYQINRLEKE QKDTEAASRA SFRKHFVRQC QELHRQLDDH  60
   61 RNRIEKAKTD ETYKKENALE QLDKLKQRLT ALSPEKEQLS FSVSVDSQSE EEKPKMAAIG 120
  121 RRKSTMYND

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1zwwA
Description: Crystal structure of endophilin-A1 BAR domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [130-456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DESEDSDNDS EIIETDVQLD DPLPSQPQPP QQQHQQPQPK PRQPITITKP LESKTLNERQ  60
   61 ELDEVISRLQ NPSRGDSGEV MEPVVVRGNV FVAIDSWDAE AEGDLELIKG KKYRITQTRS 120
  121 DGWWTALDEY GQRGLVPKTY LQHVKEKPKN VPSKVSSRLG VRDSVIGIST TTDPSRREAN 180
  181 RQASRVDDCL GKAYDNDTHL SLVCHMAPRL STSNIGFHDL FWSHYKDQVY KRTVHISKII 240
  241 RLVRFEKMPL IEHKALVRMA LVDITNPKST QIVSNVHTLV PRVKSSTWYF EKKESQTRSC 300
  301 IEFSDFVLRS NYRSPTVVLV VEASHLV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.522879
Match: 2h8hA
Description: No description for 2h8hA was found.

Predicted Domain #3
Region A:
Residues: [457-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTQIGIEEKS LGHTYLRLII DDKAVPSRTN VLYLDDEVMT KMKLPEASKR RVLVQVMDVP  60
   61 KDKVSYVDSL PDVIVFN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1djgA
Description: Phosphoinositide-specific phospholipase C, isozyme D1 (PLC-D!); PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain; Phospholipase C isozyme D1 (PLC-D1)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [534-682]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ALYLPFFHFY RRRAGTILIR DNRNPLSAEF ISDPLLSVFP FVCDQHDIMD IMLKIWKTKK  60
   61 KVLAKKNEAE QTAEFFQTFL HTAFFIHGIR MISYDVKDDL TLSIRQQTMQ RFVDALNKGL 120
  121 FKQFIADQQC KPINIIDYSL DLLGNHSID

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle