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Protein Overview: nhr-108

General Information:
Name(s) found: nhr-108 / CE15962 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00003698 locus:nhr-108 Nuclear hormone receptor family member nhr-108 status:Confirmed UniProt:O45449 protein_id:CAB04290.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 338 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKKSENQPC MVCGEISYSI RFGAVSCRAC AEFFRRKIVS KARIPKRCNG ACDLGKYHRK  60
   61 TCQSCRFQKC LKIGMLEKVV ASRTPVNRRS ENNQTILSGL EKAYDKLENS RDNVFDRKNK 120
  121 IPKYCNHQEL DDMFEIDIKL ISTHFIQFFE SKSSLENNQN KVLSTHFIIR FSLLEVAFRA 180
  181 FGKPTYILPN NDIIDVSKLD KVYQHLETGE DERGKNSQVI LQRFWQMNEK TMKTEVFPVN 240
  241 LDQSEFLFLC ALIYWDFGIE NQSEKCLEEC QRMRTQVLKE LTEYEKSNYP ENELRVAQVI 300
  301 GILQALQKTL DVIQHSGYIS NVYNLKGKQC PLYEATNE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..93] PSI-BLAST 21.522879 Steroid hormone receptor Err2
    2 View Details [94..338] PSI-BLAST 38.30103 hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.18770607371139 bayes_pls_golite062009
  • protein binding
    		•  0.699012253331291 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle