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Protein Overview: mec-7

General Information:
Name(s) found: mec-7 / CE15257 [WormBase]
Description(s) found:
Found 23 descriptions.
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  • WBGene00003171 locus:mec-7 Tubulin beta-1 chain status:Confirmed UniProt:P12456 protein_id:CCD67558.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 441 amino acids

    Gene Ontology:
    Cellular Component: neuronal cell body [IDALink to PubMed article]
    protein complex [IEALink to PubMed article]
    neuron projection [IDALink to PubMed articleLink to PubMed article]
    microtubule [IEALink to PubMed article]
    Biological Process: mechanosensory behavior [IMPLink to PubMed article]
    protein polymerization [IEALink to PubMed article]
    cytoplasmic microtubule organization [IMPLink to PubMed article]
    response to mechanical stimulus [IMPLink to PubMed article]
    detection of mechanical stimulus involved in sensory perception [IMPLink to PubMed article]
    microtubule-based process [IEALink to PubMed article]
    Molecular Function: GTP binding [IEALink to PubMed article]
    GTPase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREIVHIQAG QCGNQIGSKF WEVISDEHGI DPSGQYVGDS DLQLERINVY YNEAGSNKYV  60
   61 PRAVLVDLEP GTMDSVRSGP FGQLFRPDNY VFGQSGAGNN WAKGHYTEGA ELVDNVLDVV 120
  121 RKEAESTDCL QGFQLTHSLG GGTGSGMGTL LISKIREEYP DRIMNTFSVV PSPKVSDTVV 180
  181 EPYNATLSVH QLVENTDSTF CIDNEALYDI CFRTLKLTTP TYGDLNHLVS ATMSGVTTCL 240
  241 RFPGQLNADL RKLAVNMVPF PRLHFFMPGF APLTSRSNQQ YRAITVPELT QQCFDAKNMM 300
  301 AACDPRHGRY LTAAAIFRGR MSMKEVDEQM LNIQNKNSSY FVDWIPNNVK TAVCDIPPRG 360
  361 LKMSATFIGN STAIQELFKR ISEQFTAMFR RKAFLHWYTG EGMDEMEFTE AESNMNDLVS 420
  421 EYQQYQEAAA DEDAAEAFDG E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..441] PSI-BLAST 165.0 Tubulin:stathmin-like domain complex


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle