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Protein Overview: nekl-2

General Information:
Name(s) found: nekl-2 / CE15235 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00022631 locus:nekl-2 status:Confirmed UniProt:O01775 protein_id:CCD64899.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 357 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    collagen and cuticulin-based cuticle development [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: magnesium ion binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNYEKVRVV GRGAFGVCWL CRGKNDASHQ KVIIKLINTH GMTEKEENSI QSEVNLLKKV  60
   61 QHPLIIGYID SFIMDNQLGI VMQYAEGGTL ERLINDQRAI KDSNMREYFP EKTVLDYFTQ 120
  121 ILIALNHMHQ KNIVHRDLKP QNILMNRRKT VLKLSDFGIS KELGTKSAAS TVIGTPNYLS 180
  181 PEICESRPYN QKSDMWSLGC VLYELLQLER AFDGENLPAI VMKITRSKQN PLGDHVSNDV 240
  241 KMLVENLLKT HTDKRPDVSQ LLSDPLVLPY LISIHCDLGR IEPPPTDKRK PSASLSSRLR 300
  301 TYPTQSTLRP YSLSSNAPTT HLTQLTPMPS HIDSGFFSSG RTSNQRTQSR SQVHSKY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..357] PSI-BLAST 72.09691 Crystal Structure of the Auto-Inhibited Kinase Domain of Calcium/Calmodulin Activated Kinase II


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle