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Protein Overview: dhod-1

General Information:
Name(s) found: dhod-1 / CE14420 [WormBase]
Description(s) found:
Found 23 descriptions.
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  • WBGene00020932 locus:dhod-1 status:Confirmed UniProt:O01815 protein_id:CCD68985.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 411 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    Biological Process: 'de novo' pyrimidine base biosynthetic process [IEALink to PubMed article]
    UMP biosynthetic process [IEALink to PubMed article]
    Molecular Function: dihydroorotate dehydrogenase activity [IEALink to PubMed article]
    dihydroorotate oxidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQNAEQKYI YSKLPPGAIS KSTVIVLATG IASYTALELL YGSETFYKKA VMPMVHKFVD  60
   61 GEDSHRWAVR AASWGLLPRF GWNRKEYPEL KCELFGREFK NPIGLAAGFD KDGQAITQLA 120
  121 KNSGFGLIEI GSVTPIPQPG NNRPRVFRLL EDEGVINRYG FNSDGVGRVH QRVRSARDSW 180
  181 VPESYAYFGV NLGKNKLTED AKLDYEIGVN YFAPHCDYLV LNVSSPNTPG LRSMQKKSDL 240
  241 EKLLAYVHQA LEMHKLEKQP QVFLKIAPDL IESELKDIAQ VVTNKKFAID GIIVSNTTIA 300
  301 RPDYLRSENK TETGGLSGAP VREISTECVR KIYKLTNGQI PIIGCGGVFS GADAYEKIRA 360
  361 GASLVQLYSA FVYEGFPVIG KIKRELVELL RKDGFSHVSE AIGADHREKT K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..411] PSI-BLAST 75.045757 Rat dihydroorotate dehydrogenase (DHOD)in complex with atovaquone

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity
    		•  2.7385769437489 bayes_pls_golite062009
  • dihydroorotate dehydrogenase activity
    		•  2.73800716363956 bayes_pls_golite062009
  • dihydroorotate oxidase activity
    		•  2.35584458985229 bayes_pls_golite062009
  • catalytic activity
    		•  1.94749091175302 bayes_pls_golite062009
  • dihydropyrimidine dehydrogenase (NADP+) activity
    		•  1.76080169529176 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
    		•  0.962937319088834 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.876786102965635 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.126127705865716 bayes_pls_golite062009
  • binding
    		•  0.100344139383616 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.64

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle