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Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: dihydropyrimidine dehydrogenase (NADP+) activity
Acc: GO:0017113
Aspect: Molecular Function
Desc: Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+.
Synonyms:
  • DHPDH
  • dihydrouracil dehydrogenase (NADP)
  • dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)
  • DHU dehydrogenase activity
  • 4,5-dihydrothymine: oxidoreductase activity
  • dihydrothymine dehydrogenase activity
  • hydropyrimidine dehydrogenase activity
  • DPD
  • 5,6-dihydrouracil:NADP+ 5-oxidoreductase activity
  • dihydropyrimidine dehydrogenase activity
  • dihydrouracil dehydrogenase (NADP+) activity
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0017113 - dihydropyrimidine dehydrogenase (NADP+) activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle