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Protein Overview: gad-1

General Information:
Name(s) found: gad-1 / CE13295 [WormBase]
Description(s) found:
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  • WBGene00001513 locus:gad-1 Gastrulation defective protein 1 status:Confirmed UniProt:O16519 protein_id:CCD72040.1 [WormBase]
  • pir||T31906 hypothetical protein T05H4.14 - Caenorhabditis elegans [NCBI NR]
  • gi|74956881|sp|O16519.1|GAD1_CAEEL RecName: Full=Gastrulation defective protein 1 [NCBI NR]
  • gi|2315521|gb|AAB66019.1| Gastrulation defective protein 1, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17563948|ref|NP_504635.1| GAstrulation Defective family member (gad-1) [Caenorhabditis elegans] [NCBI NR]
  • Gastrulation defective protein 1 OS=Caenorhabditis elegans GN=gad-1 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE13295 WBGene00001513 locus:gad-1 status:Partially_confirmed TR:O16519 protein_id:AAB66019.1 [wormpep150.fasta]
  • 13295 WBGene00001513 locus:gad-1 status:Partially_confirmed TR:O16519 protein_id:AAB66019.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • WD domain containing protein like, GAstrulation Defective GAD-1 (69.0 kD) (gad-1) [Caenorhabditis elegans]gi|2315521|gb|AAB66019.1| Gastrulation defective protein 1 [Caenorhabditis elegans]gi|7507240|pir||T31906 hypothetical protein T05H4.14 - Caenorhab [nrdb_11152004_Chlamydomonas]
  • locus:gad-1 status:Partially_confirmed TR:O16519 protein_id:AAB66019.1 [wormpep115.fasta.reversed]
  • CE13295 status:Partially_confirmed TR:O16519 protein_id:AAB66019.1 [wormpep80.hongbin]
  • CE13295 WBGene00001513 locus:gad-1 status:Partially_confirmed UniProt:O16519 protein_id:AAB66019.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE13295 WBGene00001513 locus:gad-1 status:Partially_confirmed UniProt:O16519 protein_id:AAB66019.1| [wormORF-contam.fasta]
  • Gastrulation defective protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • GAstrulation Defective family member (gad-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE13295 WBGene00001513 locus:gad-1 status:Confirmed UniProt:O16519 protein_id:CCD72040.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE13295 WBGene00001513 locus:gad-1 status:Confirmed UniProt:O16519 protein_id:CCD72040.1 Gastrulation defective protein 1 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 620 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: establishment of mitotic spindle orientation [IMPLink to PubMed article]
    cell migration involved in gastrulation [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    regulation of mitotic cell cycle [IMPLink to PubMed article]
    Molecular Function: protein binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDNTAPKKN SEKKARVFDL QAMFAQTISN APRTEEPTHV PQSVSVSSKS ESGVSSSAVS  60
   61 DDEDDFMPDL PPGFQMQQSE AGPSSSRAEG PEDSDDSDFD ETEAISIIKL IPAACEAKIS 120
  121 HGTQAISALR VEPPGVRFAS GGLDYYVKLF DFQKMDMSMR YDKELLPAES HVINSLAFSP 180
  181 NGETLVVASG EAIIRLLDRA GKQWSETVRG DQYIIDLNIT KGHTATVNCV EFNPLNKNEF 240
  241 ISCSDDGSLR LWNLDDHKVI TKCINKHRKV IKTKGANGKR VSPQVCTFSP DGKWIAAGCD 300
  301 DGSVQAWKYG SQYVNVNYLV RKAHNGSITS IAFSPDSKRL LSRGFDDTLK MWSLDNPKEP 360
  361 LLVKTGLENA FKSTDCGFSP RAEVVFTGTS SPNKDTPGTL QFFDPMTFDL VYKIDYPGIS 420
  421 CHRIQWHPRL NQIIAGLSDG TIHVYYDQTM SQRGVMSCVT KPLKRNRASE VVREDMVLSP 480
  481 LSLEMFQPRG EEGEEKEVTG WRIKKYLRMQ DNKLRPEFRK PADMPINGKS ANGRVAASGG 540
  541 SLHSYLAKQI GTARNAEFLK DTDVRASILK HAKDAEENPL YIDKAYRKTQ PKKIFQETAV 600
  601 EPEDQDDEEL QPVFKMPRTK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..505] PSI-BLAST 56.0 Actin interacting protein 1
    2 View Details [506..620] PSI-BLAST 22.69897 No description for 2pm9A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  3.86142918698875 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.1056443224755 bayes_pls_golite062009
  • tubulin binding
    		•  2.76945430061825 bayes_pls_golite062009
  • microtubule binding
    		•  2.72684103222924 bayes_pls_golite062009
  • dynein binding
    		•  2.54821997913979 bayes_pls_golite062009
  • protein binding
    		•  2.26925404328312 bayes_pls_golite062009
  • actin filament binding
    		•  2.0735069176589 bayes_pls_golite062009
  • dynactin binding
    		•  1.99805820148456 bayes_pls_golite062009
  • binding
    		•  1.99637157021613 bayes_pls_golite062009
  • chromatin binding
    		•  1.47324631246337 bayes_pls_golite062009
  • RNA binding
    		•  1.47267432096753 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  1.01166033978052 bayes_pls_golite062009
  • myosin binding
    		•  0.989691178611801 bayes_pls_golite062009
  • transporter activity
    		•  0.692270256454453 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.485054404024611 bayes_pls_golite062009
  • dynein intermediate chain binding
    		•  0.443846546939402 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.367729389382533 bayes_pls_golite062009
  • signal transducer activity
    		•  0.367729389382533 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  0.231534552000461 bayes_pls_golite062009
    		• 0.13154833491231 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.121183207943714 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.118975415284669 bayes_pls_golite062009
  • myosin II binding
    		•  0.0145748031956598 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.00585398682921312 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle