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View Structure Prediction Details

Protein: gad-1
Organism: Caenorhabditis elegans
Length: 620 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gad-1.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
627.0 [0..2] [613..1183]

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Predicted Domain #1
Region A:
Residues: [1-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDNTAPKKN SEKKARVFDL QAMFAQTISN APRTEEPTHV PQSVSVSSKS ESGVSSSAVS  60
   61 DDEDDFMPDL PPGFQMQQSE AGPSSSRAEG PEDSDDSDFD ETEAISIIKL IPAACEAKIS 120
  121 HGTQAISALR VEPPGVRFAS GGLDYYVKLF DFQKMDMSMR YDKELLPAES HVINSLAFSP 180
  181 NGETLVVASG EAIIRLLDRA GKQWSETVRG DQYIIDLNIT KGHTATVNCV EFNPLNKNEF 240
  241 ISCSDDGSLR LWNLDDHKVI TKCINKHRKV IKTKGANGKR VSPQVCTFSP DGKWIAAGCD 300
  301 DGSVQAWKYG SQYVNVNYLV RKAHNGSITS IAFSPDSKRL LSRGFDDTLK MWSLDNPKEP 360
  361 LLVKTGLENA FKSTDCGFSP RAEVVFTGTS SPNKDTPGTL QFFDPMTFDL VYKIDYPGIS 420
  421 CHRIQWHPRL NQIIAGLSDG TIHVYYDQTM SQRGVMSCVT KPLKRNRASE VVREDMVLSP 480
  481 LSLEMFQPRG EEGEEKEVTG WRIKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.0
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 3.86142918698875 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
actin filament binding 2.0735069176589 bayes_pls_golite062009
dynactin binding 1.99805820148456 bayes_pls_golite062009
binding 1.99637157021613 bayes_pls_golite062009
chromatin binding 1.47324631246337 bayes_pls_golite062009
RNA binding 1.47267432096753 bayes_pls_golite062009
microtubule plus-end binding 1.01166033978052 bayes_pls_golite062009
myosin binding 0.989691178611801 bayes_pls_golite062009
transporter activity 0.692270256454453 bayes_pls_golite062009
DNA-dependent ATPase activity 0.485054404024611 bayes_pls_golite062009
dynein intermediate chain binding 0.443846546939402 bayes_pls_golite062009
molecular transducer activity 0.367729389382533 bayes_pls_golite062009
signal transducer activity 0.367729389382533 bayes_pls_golite062009
myosin heavy chain kinase activity 0.231534552000461 bayes_pls_golite062009
0.13154833491231 bayes_pls_golite062009
substrate-specific transporter activity 0.121183207943714 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
myosin II binding 0.0145748031956598 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [506-620]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YLRMQDNKLR PEFRKPADMP INGKSANGRV AASGGSLHSY LAKQIGTARN AEFLKDTDVR  60
   61 ASILKHAKDA EENPLYIDKA YRKTQPKKIF QETAVEPEDQ DDEELQPVFK MPRTK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.69897
Match: 2pm9A
Description: No description for 2pm9A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle