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Protein Overview: mei-2

General Information:
Name(s) found: mei-2 / CE11320 [WormBase]
Description(s) found:
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  • WBGene00003184 locus:mei-2 Meiotic spindle formation protein 2 status:Confirmed UniProt:O44740 protein_id:CCD71480.1 [WormBase]
  • pir||T32747 hypothetical protein F57B10.12 - Caenorhabditis elegans [NCBI NR]
  • gi|7407667|gb|AAF62184.1|AF248052_1 MEI-2 [Caenorhabditis elegans] [NCBI NR]
  • gi|60389879|sp|O44740.1|MEI2_CAEEL RecName: Full=Meiotic spindle formation protein 2 [NCBI NR]
  • gi|2773212|gb|AAB96729.1| Defective meiosis protein 2 [Caenorhabditis elegans] [NCBI NR]
  • gi|17508423|ref|NP_491894.1| defective MEIosis family member (mei-2) [Caenorhabditis elegans] [NCBI NR]
  • Meiotic spindle formation protein 2 OS=Caenorhabditis elegans GN=mei-2 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE11320 WBGene00003184 locus:mei-2 status:Confirmed SW:O44740 protein_id:AAB96729.1 [wormpep150.fasta]
  • 11320 WBGene00003184 locus:mei-2 status:Confirmed TR:O44740 protein_id:AAB96729.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • microtubule severing protein essential for female meiotic spindle function; C-terminal region is similar to katanin p80, defective MEIosis MEI-2 (31.5 kD) (mei-2) [Caenorhabditis elegans]gi|2773212|gb|AAB96729.1| Defective meiosis protein 2 [Caenorhabdit [nrdb_11152004_Chlamydomonas]
  • CE11320 WBGene00003184 locus:mei-2 status:Confirmed TR:O44740 protein_id:AAB96729.1 [wormpep132.fasta]
  • 11320 WBGene00003184 locus:mei-2 status:Confirmed SW:O44740 protein_id:AAB96729.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:mei-2 status:Confirmed TR:O44740 protein_id:AAB96729.1 [wormpep115.fasta.reversed]
  • CE11320 locus:mei-2 status:Confirmed [wormpep80.hongbin]
  • CE11320 WBGene00003184 locus:mei-2 status:Confirmed UniProt:O44740 protein_id:AAB96729.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE11320 WBGene00003184 locus:mei-2 status:Confirmed UniProt:O44740 protein_id:AAB96729.1| [wormORF-contam.fasta]
  • MEI-2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Meiotic spindle formation protein 2 [nr-271106-contam.fasta]
  • defective MEIosis family member (mei-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Defective meiosis protein 2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE11320 WBGene00003184 locus:mei-2 status:Confirmed UniProt:O44740 protein_id:CCD71480.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE11320 WBGene00003184 locus:mei-2 status:Confirmed UniProt:O44740 protein_id:CCD71480.1 Meiotic spindle formation protein 2 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 280 amino acids

    Gene Ontology:
    Cellular Component: spindle pole [IDALink to PubMed article]
    condensed nuclear chromosome [IDALink to PubMed article]
    Biological Process: embryonic development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    microtubule depolymerization [IDALink to PubMed article]
    meiotic spindle organization [IMPLink to PubMed article]
    meiosis [IMPLink to PubMed article]
    Molecular Function: protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGLDDRKKL THAKNRKPLN DIPKSAENRP NTRSTSSRRG AEKDVPITFI GSSRTVKADL  60
   61 PEFTNTRSRR PLHSESKKEL SRNPVSRGEE HSSSLPKSSP ESSVSVMSSN ASLWSACTEE 120
  121 VNKIGVCAKR ESRNLRVYKM KSFTSNMEQI LSNDNQLAPT VIRILNSRNS WCLNSCHACL 180
  181 TFIMENITSD NYGKRSACLK ALASITNSLL DTIIGFASTK TRRIGVDVVA EERAAKATEC 240
  241 IHNFRKIVKN RDKIYKQIDQ ETIYKLDAIL ERLKKVSSHK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..98] MSA 7.035997 View MSA. No confident structure predictions are available.
    2 View Details [99..280] MSA 10.032991 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle