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Protein Overview: CE10512

General Information:
Name(s) found: CE10512 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00018473 locus:cima-1 status:Confirmed UniProt:O44130 protein_id:CCD63788.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 543 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: inorganic anion transport [IEALink to PubMed article]
    drug transport [IEALink to PubMed article]
    phosphate transport [IEALink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: inorganic anion transmembrane transporter activity [IEALink to PubMed article]
    phosphate transmembrane transporter activity [IEALink to PubMed article]
    transporter activity [IEALink to PubMed article]
    drug transmembrane transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHTPPPNKK LSRATSLDSP PEKTIFRIDT VDLDLPSTNN GSTSMAADDQ SQDEEHSAHS  60
   61 VLFPSMRLML AAMLCCCFIT LSISSSNLAV ALICMTSCPV HGYGGTLEWQ SQQEGLVLAA 120
  121 QNAGSLIMIV TGMWADRLNG KWMVFIGLLL CCIGNLMLPL LASKSFWFAV LARISIGASD 180
  181 ACLMPAVNSL ITRWFPQAER PAAIGLISGG RQIGTLFILP TAGYLCTRKD ILDGWPAIFY 240
  241 LSATISVLVT VFWIPFGADK PAKQICISSR EKEFIETRIA CESIGKRTDR TRRVPYGAML 300
  301 HSKPLWACIF ALICHEYPLV IMLQFLPNYM RDVLEFAPTK NGIIAALPIL CLFLSKTFSS 360
  361 SLSSYLTTKL RLDKTFVCKG FNAVASAGLA ICISFVPFFN KESAFLAVFC LCGAMIFAGL 420
  421 HTPGVITAMV QIAPAFSGII TGWSFFAVAW FSIGNKILTK YIVQSGSVTE WGMVFRVSAL 480
  481 VAALPVIVFT IWGSADREWW AAPSSKCSVA SFHRPSIRDR SREMSRATSS TSLGQQSRVS 540
  541 STR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..543] PSI-BLAST 48.0 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  2.52916479889426 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.78662033436109 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • binding
    		•  1.02928844080554 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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