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Protein Overview: uri-1

General Information:
Name(s) found: uri-1 / CE09016 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00016944 locus:uri-1 status:Confirmed UniProt:Q966M4 protein_id:CCD68093.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 446 amino acids

    Gene Ontology:
    Cellular Component: prefoldin complex [IEALink to PubMed article]
    Biological Process: hermaphrodite genitalia development [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of cell proliferation [IGILink to PubMed article][IMPLink to PubMed article]
    germ-line stem cell division [IMPLink to PubMed article]
    DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis [IGILink to PubMed article]
    gamete generation [IMPLink to PubMed articleLink to PubMed article]
    protein folding [IEALink to PubMed article]
    positive regulation of mitotic cell cycle [IGILink to PubMed article][IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    DNA damage checkpoint [IGILink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of meiotic cell cycle [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: unfolded protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELYVAECN AAKARLEVET ECRRIIADNY EKVLERAKEY SKKLEAPILA KICEVGYFCG  60
   61 AHVVRTNQVT MEMGANYYGE CSIHTAEKIL DRRVSEMRRQ REEGLDSIRM LDDKIKFAQD 120
  121 NFSSVSIDGG PIEIVEKYDE EMEKLFYQNR KNKKMSQNDE QNEKIIEKNK LNGDQDHNDV 180
  181 MNRLEELEKL EQDNDEMEEA PIPKPFEVSN EDLQDLGKLE EVEEVEQDPT DKKLRFGMNE 240
  241 RLLAQPGVTQ KEMERLLDFL DTCDEESSDE EYDEDEEEGD DDEENLNNSV EELDSDDYAS 300
  301 DDNIEKSNNS DQQLKSKKIE TQVIKVEEIV EETVTKTTVK RKKSGVRFAQ QLENVKTFHQ 360
  361 TDTVEIKEED SVIETKSILR STEPTPVDRS ALEPEQKELA AMSTMTFPGE IVEKNPYECE 420
  421 PSTSRDPAPV ITEKKVSKFR ASRHRN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..120] FFAS03 3.63 Prefoldin alpha subunit
    2 View Details [121..446] PSI-BLAST 3.09691 Heavy meromyosin subfragment


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle