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Protein Overview: nhr-46

General Information:
Name(s) found: nhr-46 / CE08734 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00003636 locus:nhr-46 status:Confirmed UniProt:H2KZB8 protein_id:CCD67373.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 528 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSDWSTDFF HQSQTPNPYP PIVQQQQQPP HTSSSFFNTN HQLNSHYSSP IHQPPTSLHQ  60
   61 PIPMMQNQFK ASPPQSDQET APTTPGSGSG GQMKGERCVG CGSESAIRVH YGASSCHGCK 120
  121 AFFRRSVFEG RVYMCSADNH CDITNESRNR CRACRLRNCL EGGMNPKHVR EERSKIERMP 180
  181 GNTCTVSAAN GVSHSSSAAS ASPEHKFSFS LSTIAPSTST GSFSSGSQPA PIESTNSSGS 240
  241 EAEVLDRKLI QENQLTLFMV ALEKQTEQLT DDDVKDNDVM GAWSRDITLT FGLQHPQMVI 300
  301 KRLPLKYSCD RIMEAADLYL SWYRSFVFAA DWAMGIPEFR VLPLADQTTL FKQNFMAFGW 360
  361 ITFAYKCFEL KQHLTGMPLG NGAYIPYNDE DQKKLPERWA QTYGVVCRKL IDLIVKAMIE 420
  421 LQITEEEYCL IKTISLFQQD CILSEAGQGI CSRMRDRLLD ALSAHIEKRY PYHTTSQRMT 480
  481 RALKISLMLP SFSHIGQVES TLITQLTAAD LHQLSGVPME ICTAQTTL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..89] deduced N/A No confident structure predictions are available.
    2 View Details [90..235] PSI-BLAST 17.522879 No description for 2hanB was found.
    3 View Details [236..528] PSI-BLAST 56.0 LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.270879137859077 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  1.15996699473685 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.46162010671465 bayes_pls_golite062009
  • protein binding
    		•  0.33427459029264 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.15459949087509 bayes_pls_golite062009
  • DNA binding
    		•  0.14395376162921 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle