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Protein Overview: CE07462

General Information:
Name(s) found: CE07462 [WormBase]
Description(s) found:
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  • WBGene00020146 locus:got-1.2 Probable aspartate aminotransferase, cytoplasmic status:Confirmed UniProt:Q22067 protein_id:CCD68837.1 [WormBase]
  • pir||T29857 probable aspartate transaminase (EC 2.6.1.1) T01C8.5 [similarity] - Caenorhabditis elegans [NCBI NR]
  • gi|2492843|sp|Q22067.1|AATC_CAEEL RecName: Full=Probable aspartate aminotransferase, cytoplasmic; AltName: Full=Transaminase A; AltName: Full=Glutamate oxaloacetate transaminase 1 [NCBI NR]
  • gi|17569539|ref|NP_510709.1| hypothetical protein T01C8.5 [Caenorhabditis elegans] [NCBI NR]
  • gi|1326254|gb|AAB00578.1| Hypothetical protein T01C8.5 [Caenorhabditis elegans] [NCBI NR]
  • Probable aspartate aminotransferase, cytoplasmic OS=Caenorhabditis elegans GN=got-1.2 PE=3 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE07462 WBGene00020146 aminotransferase status:Confirmed SW:Q22067 protein_id:AAB00578.1 [wormpep150.fasta]
  • 07462 WBGene00020146 aminotransferase status:Confirmed SW:Q22067 protein_id:AAB00578.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • aspartate aminotransferase (45.5 kD) (XR406) [Caenorhabditis elegans]gi|1326254|gb|AAB00578.1| Hypothetical protein T01C8.5 [Caenorhabditis elegans]gi|7506853|pir||T29857 probable aspartate transaminase (EC 2.6.1.1) T01C8.5 [similarity] - Caenorhabditis [nrdb_11152004_Chlamydomonas]
  • aminotransferase status:Confirmed SW:Q22067 protein_id:AAB00578.1 [wormpep115.fasta.reversed]
  • CE07462 aminotransferase status:Confirmed SW:Q22067 protein_id:AAB00578.1 [wormpep80.hongbin]
  • CE07462 WBGene00020146 aminotransferase status:Confirmed UniProt:Q22067 protein_id:AAB00578.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE07462 WBGene00020146 aminotransferase status:Confirmed UniProt:Q22067 protein_id:AAB00578.1| [wormORF-contam.fasta]
  • T01C8.5 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein T01C8.5 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Probable aspartate aminotransferase, cytoplasmic (Transaminase A) (Glutamate oxaloacetate transaminase 1) [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE07462 WBGene00020146 locus:got-1.2 aminotransferase status:Confirmed UniProt:Q22067 protein_id:CCD68837.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE07462 WBGene00020146 locus:got-1.2 status:Confirmed UniProt:Q22067 protein_id:CCD68837.1 Probable aspartate aminotransferase, cytoplasmic [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 408 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: positive regulation of growth rate [IMPLink to PubMed article]
    biosynthetic process [IEALink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEALink to PubMed article]
    transferase activity, transferring nitrogenous groups [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFFDGIPVA PPIEVFHKNK MYLDETAPVK VNLTIGAYRT EEGQPWVLPV VHETEVEIAN  60
   61 DTSLNHEYLP VLGHEGFRKA ATELVLGAES PAIKEERSFG VQCLSGTGAL RAGAEFLASV 120
  121 CNMKTVYVSN PTWGNHKLVF KKAGFTTVAD YTFWDYDNKR VHIEKFLSDL ESAPEKSVII 180
  181 LHGCAHNPTG MDPTQEQWKL VAEVIKRKNL FTFFDIAYQG FASGDPAADA WAIRYFVDQG 240
  241 MEMVVSQSFA KNFGLYNERV GNLTVVVNNP AVIAGFQSQM SLVIRANWSN PPAHGARIVH 300
  301 KVLTTPARRE QWNQSIQAMS SRIKQMRAAL LRHLMDLGTP GTWDHIIQQI GMFSYTGLTS 360
  361 AQVDHLIANH KVFLLRDGRI NICGLNTKNV EYVAKAIDET VRAVKSNI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..408] PSI-BLAST 86.69897 Aspartate aminotransferase, AAT

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  6.52158261185762 bayes_pls_golite062009
  • phosphatidylserine decarboxylase activity
    		•  3.52333113038086 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.46601963907552 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.46601963907552 bayes_pls_golite062009
  • transferase activity
    		•  1.44093490824786 bayes_pls_golite062009
  • glutamate decarboxylase activity
    		•  1.34215658716536 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • 4-aminobutyrate transaminase activity
    		•  1.11017195698597 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.977210827616757 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.892872530648552 bayes_pls_golite062009
  • binding
    		•  0.892049641082766 bayes_pls_golite062009
  • N-succinyltransferase activity
    		•  0.87264568471543 bayes_pls_golite062009
  • DNA binding
    		•  0.803965264969424 bayes_pls_golite062009
  • N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
    		•  0.753443687983955 bayes_pls_golite062009
  • vitamin binding
    		•  0.66463470119531 bayes_pls_golite062009
  • transcription factor activity
    		•  0.597417107954964 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.50269055590758 bayes_pls_golite062009
  • alanine-glyoxylate transaminase activity
    		•  0.48682493494502 bayes_pls_golite062009
  • hydrolase activity
    		•  0.343938599116946 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • ligase activity
    		•  0.103307018783573 bayes_pls_golite062009
  • aromatic-amino-acid:2-oxoglutarate aminotransferase activity
    		•  0.0916183433120769 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.0833010353195099 bayes_pls_golite062009
  • amine binding
    		•  0.00719250700539997 bayes_pls_golite062009
  • kynureninase activity
    		•  0.0041576792340694 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle