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Protein Overview: aak-2

General Information:
Name(s) found: aak-2 / CE07458 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00020142 locus:aak-2 5'-AMP-activated protein kinase catalytic subunit alpha-2 status:Confirmed UniProt:Q95ZQ4 protein_id:CCD68835.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 562 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: signal transduction [IEALink to PubMed article]
    determination of adult lifespan [IMPLink to PubMed article]
    protein amino acid phosphorylation [IDALink to PubMed article][IEALink to PubMed article]
    Molecular Function: magnesium ion binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    non-membrane spanning protein tyrosine kinase activity [IEALink to PubMed article]
    protein kinase activity [IDALink to PubMed article][IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPGGETST KQQQELKAQI KIGHYILKET LGVGTFGKVK VGIHETTQYK VAVKILNRQK  60
   61 IKSLDVVGKI RREIQNLSLF RHPHIIRLYQ VISTPSDIFM IMEHVSGGEL FDYIVKHGRL 120
  121 KTAEARRFFQ QIISGVDYCH RHMVVHRDLK PENLLLDEQN NVKIADFGLS NIMTDGDFLR 180
  181 TSCGSPNYAA PEVISGKLYA GPEVDVWSCG VILYALLCGT LPFDDEHVPS LFRKIKSGVF 240
  241 PTPDFLERPI VNLLHHMLCV DPMKRATIKD VIAHEWFQKD LPNYLFPPIN ESEASIVDIE 300
  301 AVREVTERYH VAEEEVTSAL LGDDPHHHLS IAYNLIVDNK RIADETAKLS IEEFYQVTPN 360
  361 KGPGPVHRHP ERIAASVSSK ITPTLDNTEA SGANRNKRAK WHLGIRSQSR PEDIMFEVFR 420
  421 AMKQLDMEWK VLNPYHVIVR RKPDAPAADP PKMSLQLYQV DQRSYLLDFK SLADEESGSA 480
  481 SASSSRHASM SMPQKPAGIR GTRTSSMPQA MSMEASIEKM EVHDFSDMSC DVTPPPSPGG 540
  541 AKLSQTMQFF EICAALIGTL AR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..294] PSI-BLAST 82.221849 No description for 2h6dA was found.
    2 View Details [295..390] deduced N/A No confident structure predictions are available.
    3 View Details [391..562] PSI-BLAST 17.154902 No description for 2v8qA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle