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Protein Overview: hpl-1

General Information:
Name(s) found: hpl-1 / CE06164 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00001995 locus:hpl-1 status:Confirmed UniProt:G5EET5 protein_id:CAA94152.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 184 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    chromatin [IEALink to PubMed article]
    Biological Process: negative regulation of vulval development [IGILink to PubMed article]
    germ cell development [IGILink to PubMed article]
    gonad development [IGILink to PubMed article]
    negative regulation of Ras protein signal transduction [IGILink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    regulation of cell differentiation [IGILink to PubMed article]
    nematode larval development [IGILink to PubMed article]
    positive regulation of growth rate [IGILink to PubMed article]
    chromatin assembly or disassembly [IEALink to PubMed article]
    reproduction [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: chromatin binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRQNPVRST RGNSLRAREA QQAQDAPLFQ ESSSNVFVVE KVLNKRLTRG GSEYYIKWQG  60
   61 FPESECSWEP IENLQCDRMI QEYEKEAAKR TTRKRRYSPQ PSTSSSAELQ PSTSDEWAGK 120
  121 TLKTIIGITK APGELHFLCK FSDDSVHLIP LREANVRFPS QVIKFYETRL VLQGVSPTIP 180
  181 GGMS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..184] PSI-BLAST 9.30103 Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and phosphothreonine 3

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.72796089835126 bayes_pls_golite062009
  • chromatin binding
    		•  0.992646667007469 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.90959660710929 bayes_pls_golite062009
  • protein binding
    		•  0.89835439354196 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.29923452744967 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle