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Protein Overview: xpa-1

General Information:
Name(s) found: xpa-1 / CE06130 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00006963 locus:xpa-1 status:Confirmed UniProt:Q21302 protein_id:CAA95829.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 241 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: nucleotide-excision repair [IEALink to PubMed article]
    Molecular Function: damaged DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKRRYNPSA NEEEKIPIVE KLYRENQESD FLGGGFCDDD DEVQERREQI SEMRQKREEA  60
   61 AHNLIQAPEN CEKCDKGLMD SWLWERYNCA VCDACRDDKG EHKLLARTEV KNTYLLKDCD 120
  121 LDLRKPKLRY WAKKNPHNPR YGDMKLYLKC QIETRVLEVH GSWEDLELKK ELREQSKEVR 180
  181 SEKRFEKKLK DLRQQIRGTS GVKVDFGRPH THEFGKETHV EEDTWRRTCI TCEYEEVFEK 240
  241 L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..192] PSI-BLAST 41.0 SOLUTION STRUCTURE OF THE DNA-AND RPA-BINDING DOMAIN OF THE HUMAN REPAIR FACTOR XPA, NMR, 1 STRUCTURE
    2 View Details [193..241] MSA 1.036989 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.18770607371139 bayes_pls_golite062009
  • protein binding
    		•  0.699012253331291 bayes_pls_golite062009
  • DNA binding
    		•  0.69568583152884 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.39779340917087 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.1367607837242 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle