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View Structure Prediction Details

Protein: xpa-1
Organism: Caenorhabditis elegans
Length: 241 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for xpa-1.

Description E-value Query
Range
Subject
Range
gi|187023349, gi... - gi|39580823|emb|CAE73084.1| Hypothetical protein CBG20462 [Caenorhabditis briggsae], gi|187023349|em...
275.0 [0..1] [241..1]
XPA_MOUSE - DNA repair protein complementing XP-A cells homolog OS=Mus musculus GN=Xpa PE=1 SV=1
260.0 [0..18] [241..56]
gi|60654147 - gi|60654147|gb|AAX29766.1| xeroderma pigmentosum complementation group A [synthetic construct]
258.0 [0..30] [241..70]
gi|61357324, gi|... - gi|61357324|gb|AAX41371.1| xeroderma pigmentosum complementation group A [synthetic construct], gi|1...
XPA - xeroderma pigmentosum, complementation group A
257.0 [0..30] [241..70]
XPA_CHICK - DNA repair protein complementing XP-A cells homolog OS=Gallus gallus GN=XPA PE=2 SV=1
257.0 [0..27] [241..58]
gi|84579859, gi|... - gi|84579859|ref|NP_001033770.1| xeroderma pigmentosum, complementation group A [Bos taurus], gi|8375...
256.0 [0..4] [241..46]
gi|109110874 - gi|109110874|ref|XP_001114093.1| PREDICTED: xeroderma pigmentosum, complementation group A [Macaca m...
255.0 [0..30] [241..70]
gi|73971420 - gi|73971420|ref|XP_538745.2| PREDICTED: similar to DNA-repair protein complementing XP-A cells (Xero...
253.0 [0..19] [241..57]

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Predicted Domain #1
Region A:
Residues: [1-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKRRYNPSA NEEEKIPIVE KLYRENQESD FLGGGFCDDD DEVQERREQI SEMRQKREEA  60
   61 AHNLIQAPEN CEKCDKGLMD SWLWERYNCA VCDACRDDKG EHKLLARTEV KNTYLLKDCD 120
  121 LDLRKPKLRY WAKKNPHNPR YGDMKLYLKC QIETRVLEVH GSWEDLELKK ELREQSKEVR 180
  181 SEKRFEKKLK DL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.0
Match: 1xpaA
Description: SOLUTION STRUCTURE OF THE DNA-AND RPA-BINDING DOMAIN OF THE HUMAN REPAIR FACTOR XPA, NMR, 1 STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.18770607371139 bayes_pls_golite062009
protein binding 0.699012253331291 bayes_pls_golite062009
DNA binding 0.69568583152884 bayes_pls_golite062009
nucleic acid binding 0.39779340917087 bayes_pls_golite062009
transcription regulator activity 0.1367607837242 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [193-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQQIRGTSGV KVDFGRPHTH EFGKETHVEE DTWRRTCITC EYEEVFEKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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