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Protein Overview: gta-1

General Information:
Name(s) found: gta-1 / CE06092 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00001794 locus:gta-1 Probable 4-aminobutyrate aminotransferase, mitochondrial status:Confirmed UniProt:Q21217 protein_id:CAA93517.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 483 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: arginine metabolic process [IEALink to PubMed article]
    ectoine biosynthetic process [IEALink to PubMed article]
    biosynthetic process [IEALink to PubMed article]
    biotin biosynthetic process [IEALink to PubMed article]
    gamma-aminobutyric acid metabolic process [IEALink to PubMed article]
    Molecular Function: pyridoxal phosphate binding [IEALink to PubMed article]
    4-aminobutyrate transaminase activity [IEALink to PubMed article]
    transaminase activity [IEALink to PubMed article]
    diaminobutyrate-pyruvate transaminase activity [IEALink to PubMed article]
    adenosylmethionine-8-amino-7-oxononanoate transaminase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPRLAKSSL IQQVRGVSAI ANAEPSGPSI STSIPGPKSK ALKQEMDKVH QTTSVRFHVD  60
   61 YEKSFGNYVV DADGNALLDV YTQISSLPLG YNHPDLVKVA SQPHLITSLV SRPALGSFPR 120
  121 TDFADGISHA LTSIAPKGLK AVQTMLCGTS ANENAIKTAF IWYQAQRRGG LGPDALHLES 180
  181 CMNQQKPGTP NLSVMGFEGA FHGRSLCMLS VTRSKPIHKV DIPAFDWPIA KFPRYKYPLD 240
  241 QNVAYNKKQD QECLADVEAK ISEWKRRDND VAAIIVEPIQ AEGGDHYGSP AFFQGLRDIT 300
  301 SKHGIVFIVD EVQTGGGATG DIWAHDHWNL SSPPDMVTFS KKLLTGGYFY GEHLRVKEAY 360
  361 RIYNTWMGDP TKLLLLEKAV EVIKRDGLIE QSREVGAEFQ KRLGELQASS GGKLDQARGR 420
  421 GTFAAVDFPS GSLRDKFVDL AISNGLHCGG CGDRSLRFRP SLVYTKKHLD LTFDLLDKTL 480
  481 KGL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..483] PSI-BLAST 96.045757 4-AMINOBUTYRATE-AMINOTRANSFERASE FROM PIG

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 4-aminobutyrate transaminase activity
    		•  3.63797881096751 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  3.359406422625 bayes_pls_golite062009
  • transferase activity
    		•  2.59075614411581 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  1.85905571238884 bayes_pls_golite062009
  • adenosylmethionine-8-amino-7-oxononanoate transaminase activity
    		•  1.74778109525713 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.63055151623667 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.63055151623667 bayes_pls_golite062009
  • N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
    		•  1.4383564662931 bayes_pls_golite062009
  • glutamate decarboxylase activity
    		•  1.34215658716536 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  1.19150094103499 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.977210827616757 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.892872530648552 bayes_pls_golite062009
  • ligase activity
    		•  0.827063849687833 bayes_pls_golite062009
  • DNA binding
    		•  0.803965264969424 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase binding
    		•  0.78144409237642 bayes_pls_golite062009
  • carbon-sulfur lyase activity
    		•  0.698312655247044 bayes_pls_golite062009
  • intramolecular transferase activity, transferring amino groups
    		•  0.659071155545801 bayes_pls_golite062009
  • transcription factor activity
    		•  0.597417107954964 bayes_pls_golite062009
  • N-succinyltransferase activity
    		•  0.52897097514616 bayes_pls_golite062009
  • binding
    		•  0.49769115245722 bayes_pls_golite062009
  • ornithine-oxo-acid transaminase activity
    		•  0.311107335626334 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  0.2609065149092 bayes_pls_golite062009
  • kynureninase activity
    		•  0.242752584041108 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.15938456446406 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.103986924428507 bayes_pls_golite062009
  • sulfurtransferase activity
    		•  0.0450490929307473 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.0254276656964899 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.74

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle