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Protein Overview: dhfr-1

General Information:
Name(s) found: dhfr-1 / CE05374 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00007974 locus:dhfr-1 Putative dihydrofolate reductase status:Confirmed UniProt:Q93341 protein_id:CAB02272.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 189 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: nucleotide biosynthetic process [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    glycine biosynthetic process [IEALink to PubMed article]
    one-carbon metabolic process [IEALink to PubMed article]
    Molecular Function: thymidylate synthase activity [IEALink to PubMed article]
    NADP or NADPH binding [IEALink to PubMed article]
    dihydrofolate reductase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKMNLIVAM DAEGGIGKNG VLPWRIKKDM QYFASVTKNV SDQSKRNAVL MGRKCWESIP  60
   61 VTRRPLAGRL NIVLSRQLPA QKSDDYIVVN SLEAAMKLLS EPPFVDSIET IWNIGGAEIY 120
  121 DLALRENLVD EIHLTRIFKN FEADVHLKSL DFSKMEKVQN AEVSSENSEI FEENGLKFEF 180
  181 CKWKVVENH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..189] PSI-BLAST 56.30103 No description for 2fzjA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle