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Protein Overview: pptr-2

General Information:
Name(s) found: pptr-2 / CE05279 [WormBase]
Description(s) found:
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  • WBGene00007554 locus:pptr-2 status:Confirmed UniProt:Q17948 protein_id:CAA98422.1 [WormBase]
  • pir||T19241 hypothetical protein C13G3.3a - Caenorhabditis elegans [NCBI NR]
  • gi|3874266|emb|CAA98422.1| C. elegans protein C13G3.3a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17557912|ref|NP_505808.1| Protein Phosphatase 2A (Two A) Regulatory subunit family member (pptr-2) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE05279 WBGene00007554 proteion phosphatase status:Confirmed TR:Q17948 protein_id:CAA98422.1 [wormpep150.fasta]
  • 05279 WBGene00007554 proteion phosphatase status:Confirmed TR:Q17948 protein_id:CAA98422.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • delta of regulatory B56 protein phosphatase 2A Serine threonine ; pp2a B' pr61 R5 (64.4 kD) (5L508) [Caenorhabditis elegans]gi|3874266|emb|CAA98422.1| Hypothetical protein C13G3.3a [Caenorhabditis elegans]gi|7495942|pir||T19241 hypothetical protein C13G [nrdb_11152004_Chlamydomonas]
  • proteion phosphatase status:Confirmed TR:Q17948 protein_id:CAA98422.1 [wormpep115.fasta.reversed]
  • CE05279 proteion phosphatase status:Confirmed TR:Q17948 protein_id:CAA98422.1 [wormpep80.hongbin]
  • CE05279 WBGene00007554 locus:pptr-2 proteion phosphatase status:Confirmed UniProt:Q17948_CAEEL protein_id:CAA98422.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE05279 WBGene00007554 locus:pptr-2 proteion phosphatase status:Confirmed UniProt:Q17948_CAEEL protein_id:CAA98422.1| [wormORF-contam.fasta]
  • C13G3.3a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C13G3.3a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE05279 WBGene00007554 locus:pptr-2 proteion phosphatase status:Confirmed TR:Q17948 protein_id:CAA98422.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE05279 WBGene00007554 locus:pptr-2 proteion phosphatase status:Confirmed UniProt:Q17948 protein_id:CAA98422.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE05279 WBGene00007554 locus:pptr-2 status:Confirmed UniProt:Q17948 protein_id:CAA98422.1 [wormpep246-ecoli-contam.fasta]
  • Isoform of A9UJN4, Protein Phosphatase 2A (Two A) Regulatory subunit OS=Caenorhabditis elegans GN=pptr-2 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 557 amino acids

    Gene Ontology:
    Cellular Component: protein phosphatase type 2A complex [IEALink to PubMed article]
    Biological Process: signal transduction [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: protein phosphatase type 2A regulator activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPADAPPPT NIGRTNTYGG GPVIPRRERR QSSSMFNISQ NRELQRLPAI KDADPSERET  60
   61 LFIQKLRQCC VVFDFANDAL SDLKFKEVKR AALNELVDHV SGAPKGSLSD AVYPEAIGMF 120
  121 STNLFRPLSP PTNPIGAEFD PDEDEPTLEA AWPHLQLVYE FFLRFLECPD FQSQVAKRYI 180
  181 DQNFILRLLM IMDSEDPRER DFLKTTLHRI YGKFLGHRAY IRKQINNIFY SFIYETERHN 240
  241 GIAELLEILG SIINGFALPL KEEHKTFLLR VLLPLHKVKS LSVYHPQLAY CVVQFIEKDS 300
  301 SLTEPVISGM LRFWPKQHSP KEVMFLNELE EVLDVIEPNE FQKIMTPLFS QIARCVSSPH 360
  361 FQVAERALYY WNNEYVMSLV ADNARVIIPI MFPVLFKNSK SHWNKTIHGL IYNALKMFME 420
  421 MNQKLFDECS QAYQKDRVQE KTLNEEKERI WNNIEKQAMG NPQYVEVKAL FARFNPDEII 480
  481 SSRQQNGVDE NMKTSTVLSK DEILKNAVGV SSMKNDMDFG PNHKQSDFPP DEQTTRALGE 540
  541 YKRHDPFLKK VTSTDEQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..469] PSI-BLAST 1000.0 No description for 2nppB was found.
    2 View Details [470..557] MSA 1.034985 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  3.0667965351474 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  2.90442709223348 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  2.43818477885422 bayes_pls_golite062009
  • protein phosphatase type 2A regulator activity
    		•  2.4262941420561 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.13472456858224 bayes_pls_golite062009
  • phosphatase regulator activity
    		•  1.88919819318597 bayes_pls_golite062009
  • protein phosphatase regulator activity
    		•  1.7842476658781 bayes_pls_golite062009
  • protein binding
    		•  1.73688475473996 bayes_pls_golite062009
  • phosphatase activity
    		•  1.47453833246612 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  1.24670233688276 bayes_pls_golite062009
  • myosin phosphatase activity
    		•  1.2020405346133 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.13208464017585 bayes_pls_golite062009
  • hydrolase activity
    		•  0.42501390959416 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.385452858197632 bayes_pls_golite062009
  • DNA binding
    		•  0.309260217284589 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle