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Protein Overview: gspd-1

General Information:
Name(s) found: gspd-1 / CE05163 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00007108 locus:gspd-1 Glucose-6-phosphate 1-dehydrogenase status:Confirmed UniProt:Q27464 protein_id:CAA97412.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 522 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    glucose metabolic process [IEALink to PubMed article]
    Molecular Function: glucose-6-phosphate dehydrogenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MACKRHSVSD PISKDLVECL RESMQRDLKF ETPYVFVIFG ASGDLAKKKI YPTLWWLFRD  60
   61 NLLPVNIKFI GYARSDLTVF KLRESFEKNC KVRENEKCAF DDFIKKCSYV QGQYDTSEGF 120
  121 QRLQSSIDDF QKESNNQAVN RLYYLALPPS VFNVVSTELK KNCMDHGDSW TRVIIEKPFG 180
  181 HDLKSSCELS THLAKLFKED QIYRIDHYLG KEMVQNLMVM RFGNRILAPS WNRDHIASVM 240
  241 ISFKEDFGTG GRAGYFDTAG IIRDVMQNHL MQILTLVAME KPASLNAEDI RDEKVKVLKA 300
  301 AKVVELKDVV VGQYIASPEF DHPEASQGYK DDKSVPADST TPTYALAVVH INNERWEGVP 360
  361 FFLRCGKALN EKKAEVRIQF KEVSGDIYPS GELKRSELVM RVQPNEAVYM KLMTKKPGMG 420
  421 FGVEETELDL TYNNRFKEVR LPDAYERLFL EVFMGSQINF VRTDELEYAW RILTPVLEEL 480
  481 KKKKVQPVQY KFGSRGPTEG DELMKKYGFI FTGTYKWVAP KL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..522] PSI-BLAST 1000.0 Glucose 6-phosphate dehydrogenase, N-terminal domain; Glucose 6-phosphate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glucose-6-phosphate dehydrogenase activity
    		•  5.10379236186634 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • steroid dehydrogenase activity
    		•  1.75109362865449 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.55012034958204 bayes_pls_golite062009
  • DNA binding
    		•  1.30649176474402 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.21797427723368 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  1.16811519855038 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.16624046427845 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • binding
    		•  0.982999356179965 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.749202992278132 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  0.65743456407889 bayes_pls_golite062009
  • transcription factor activity
    		•  0.64823933426147 bayes_pls_golite062009
  • hydrolase activity
    		•  0.64282074902621 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.547377529205729 bayes_pls_golite062009
  • NAD or NADH binding
    		•  0.44922383360529 bayes_pls_golite062009
  • 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
    		•  0.375786741986945 bayes_pls_golite062009
  • 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
    		•  0.362878028601961 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • structural molecule activity
    		•  0.34148076461528 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.225978107187737 bayes_pls_golite062009
  • kinase activity
    		•  0.201113035937958 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.156723490409668 bayes_pls_golite062009
  • glucose binding
    		•  0.13030486887358 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.126337510738706 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  0.111651152766906 bayes_pls_golite062009
  • protein kinase activity
    		•  0.0808301652371467 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0244314674300794 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle