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Protein Overview: irk-1

General Information:
Name(s) found: irk-1 / CE04787 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00002149 locus:irk-1 inward rectifier potassium channel (IRK) status:Partially_confirmed UniProt:P52192 protein_id:CCD72424.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 505 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: potassium ion transport [IEALink to PubMed article]
    Molecular Function: inward rectifier potassium channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLDTNTITF PFFVNGLFRF QDSANSLVIQ TKMPSCAHSI SALSFLESIR TLAFTARRNS  60
   61 SPLYRKSTKK LKKSRLVGKN GICNVYNTNV PKKDRQYLRD IFTTMIDVKW RWMLMLFASA 120
  121 FVLSWSIFGT TYYLIALVHG DLSLPTPVNH TACVMNLDSV YSSFLFAVET HHTIGYGHRY 180
  181 ITTECYLAGA IVCLQAICAL LLQSFMVGIV FAKMARPKKR AETIIFSDKA VICLRDGQLC 240
  241 FLCRVGDMRN THLVEAHVRL QFITDRETNE GEIEPLHQFE MKVGPSIADD DRLFLVWPTT 300
  301 LCHVIDSRSP LYNYNQQTLM SAQFEIIVLL EGIVESTGMT AQAKTSYLPS EVLWGHRFRK 360
  361 LVTYQRSNGS YQIDYDLFHS TYPVRTPAMS PAEFYSSKPN LKDYYCHDSH EHKLEDNRSS 420
  421 DSTPLPSPSP YSYPSTPLNH FQSSSNSPVF SNNHSKFNTE AVTCEAGMLC PPTIVVQCPS 480
  481 TCASPNHMRR TRNQMDKSRT RYSIA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..61] PSI-BLAST 44.30103 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    2 View Details [62..417] PSI-BLAST 72.154902 No description for 2qksA was found.
    3 View Details [418..505] PSI-BLAST 56.0 Crystal Structure of Cytoplasmic Domains of IRK1 (Kir2.1) channel


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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