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View Structure Prediction Details

Protein: irk-1
Organism: Caenorhabditis elegans
Length: 505 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for irk-1.

Description E-value Query
Range
Subject
Range
gi|73956285 - gi|73956285|ref|XP_546667.2| PREDICTED: similar to potassium inwardly-rectifying channel J12 [Canis ...
405.0 [0..40] [481..71]

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Predicted Domain #1
Region A:
Residues: [1-61]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLDTNTITF PFFVNGLFRF QDSANSLVIQ TKMPSCAHSI SALSFLESIR TLAFTARRNS  60
   61 S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.30103
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [62-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLYRKSTKKL KKSRLVGKNG ICNVYNTNVP KKDRQYLRDI FTTMIDVKWR WMLMLFASAF  60
   61 VLSWSIFGTT YYLIALVHGD LSLPTPVNHT ACVMNLDSVY SSFLFAVETH HTIGYGHRYI 120
  121 TTECYLAGAI VCLQAICALL LQSFMVGIVF AKMARPKKRA ETIIFSDKAV ICLRDGQLCF 180
  181 LCRVGDMRNT HLVEAHVRLQ FITDRETNEG EIEPLHQFEM KVGPSIADDD RLFLVWPTTL 240
  241 CHVIDSRSPL YNYNQQTLMS AQFEIIVLLE GIVESTGMTA QAKTSYLPSE VLWGHRFRKL 300
  301 VTYQRSNGSY QIDYDLFHST YPVRTPAMSP AEFYSSKPNL KDYYCHDSHE HKLEDN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.154902
Match: 2qksA
Description: No description for 2qksA was found.

Predicted Domain #3
Region A:
Residues: [418-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSSDSTPLPS PSPYSYPSTP LNHFQSSSNS PVFSNNHSKF NTEAVTCEAG MLCPPTIVVQ  60
   61 CPSTCASPNH MRRTRNQMDK SRTRYSIA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.0
Match: 1u4fA
Description: Crystal Structure of Cytoplasmic Domains of IRK1 (Kir2.1) channel
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle