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Protein Overview: coh-1

General Information:
Name(s) found: coh-1 / CE04726 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00000591 locus:coh-1 status:Partially_confirmed UniProt:Q21306 protein_id:CCD62391.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 652 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    nuclear chromosome [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    synaptonemal complex assembly [TASLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    meiosis [IMPLink to PubMed article]
    Molecular Function: damaged DNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCHPIEFCIC TISDASAHTS SSRTSFCTPS TSHIVSPSFP ICIAAKCSRC GCVAAMFYAD  60
   61 FVLSKKGPLS KVWLAAHWEK KLSKAQIFET DVDEAVNEIM QPSQKLALRT TGHLLLGICR 120
  121 VYSRKTKYLL ADCNEAFLKI KLVFRSGALD QPNPVLPTFS IQDIYGDFGD NVLPEFDEEE 180
  181 LNHAPICQSR LDDITLKEDI PQKFTYNYGE PLEDDDFGEI AAGVGPEDYY RLMEDVNKMD 240
  241 LEMELARDAA TTSDNLFGRE REPTPFLNDA HAPGNAIFGD EDFAGGDMDD DDHNVQGSSG 300
  301 FTDNNAMHME DMDYESGNTM MRGETPLRSD TPNTFRAPSP APSIAPSVAT SVSAMEHDTI 360
  361 ESYYERQAQK RAMQKEQNMR KRRVDDVKMI TGEEMKGNMA DFSDILTRLD LAPPSRKLMM 420
  421 GKKRSHAEYM HHNPGMIGFS KNKQFIRKYQ SYLVVTKHDD VDEKNEWIKN ALGLREIGEE 480
  481 ELQQQQQEMD MHVQDDSSYV DDFDEVPPLD FDQLDMMDMP QSMDDINMVD DDVPQRNPLS 540
  541 PFAPMVEDEE MSPSEKRKKR DEEKEEPETD EDNRWSKRTH ALLQNIATKL ENQNGQVELD 600
  601 EMLKKGTSRK VAAAKFYSLL CLKKNQCIDI EQKEPYGDIM IKAGPNININ TI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..207] Pfam 60.568636 No description for PF04825.4 was found. No confident structure predictions are available.
    2 View Details [208..432] MSA 1.161993 View MSA. No confident structure predictions are available.
    3 View Details [433..559] deduced N/A No confident structure predictions are available.
    4 View Details [560..652] PSI-BLAST 9.0 Sc Smc1hd:Scc1-C complex, ATPgS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  2.04123976602801 bayes_pls_golite062009
  • DNA binding
    		•  1.24351754120608 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.973857124068741 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.802843603200847 bayes_pls_golite062009
  • transcription factor activity
    		•  0.76402352618699 bayes_pls_golite062009
  • protein binding
    		•  0.058151715836892 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle