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View Structure Prediction Details

Protein: coh-1
Organism: Caenorhabditis elegans
Length: 652 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for coh-1.

Description E-value Query
Range
Subject
Range
gi|73974375 - gi|73974375|ref|XP_861017.1| PREDICTED: similar to Double-strand-break repair protein rad21 homolog ...
450.0 [0..56] [649..1]

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Predicted Domain #1
Region A:
Residues: [1-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCHPIEFCIC TISDASAHTS SSRTSFCTPS TSHIVSPSFP ICIAAKCSRC GCVAAMFYAD  60
   61 FVLSKKGPLS KVWLAAHWEK KLSKAQIFET DVDEAVNEIM QPSQKLALRT TGHLLLGICR 120
  121 VYSRKTKYLL ADCNEAFLKI KLVFRSGALD QPNPVLPTFS IQDIYGDFGD NVLPEFDEEE 180
  181 LNHAPICQSR LDDITLKEDI PQKFTYN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 60.568636
Match: PF04825.4
Description: No description for PF04825.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [208-432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGEPLEDDDF GEIAAGVGPE DYYRLMEDVN KMDLEMELAR DAATTSDNLF GREREPTPFL  60
   61 NDAHAPGNAI FGDEDFAGGD MDDDDHNVQG SSGFTDNNAM HMEDMDYESG NTMMRGETPL 120
  121 RSDTPNTFRA PSPAPSIAPS VATSVSAMEH DTIESYYERQ AQKRAMQKEQ NMRKRRVDDV 180
  181 KMITGEEMKG NMADFSDILT RLDLAPPSRK LMMGKKRSHA EYMHH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [433-559]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPGMIGFSKN KQFIRKYQSY LVVTKHDDVD EKNEWIKNAL GLREIGEEEL QQQQQEMDMH  60
   61 VQDDSSYVDD FDEVPPLDFD QLDMMDMPQS MDDINMVDDD VPQRNPLSPF APMVEDEEMS 120
  121 PSEKRKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [560-652]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDEEKEEPET DEDNRWSKRT HALLQNIATK LENQNGQVEL DEMLKKGTSR KVAAAKFYSL  60
   61 LCLKKNQCID IEQKEPYGDI MIKAGPNINI NTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.0
Match: 1w1wE
Description: Sc Smc1hd:Scc1-C complex, ATPgS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.04123976602801 bayes_pls_golite062009
DNA binding 1.24351754120608 bayes_pls_golite062009
transcription regulator activity 0.973857124068741 bayes_pls_golite062009
nucleic acid binding 0.802843603200847 bayes_pls_golite062009
transcription factor activity 0.76402352618699 bayes_pls_golite062009
protein binding 0.058151715836892 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle