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Protein Overview: cht-1

General Information:
Name(s) found: cht-1 / CE03923 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00000503 locus:cht-1 Probable endochitinase status:Partially_confirmed UniProt:Q11174 protein_id:CCD63028.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 617 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEALink to PubMed article]
    Biological Process: carbohydrate metabolic process [IEALink to PubMed article]
    chitin catabolic process [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    chitin metabolic process [IEALink to PubMed article]
    Molecular Function: chitinase activity [IEALink to PubMed article]
    chitin binding [IEALink to PubMed article]
    hydrolase activity, hydrolyzing O-glycosyl compounds [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLGKFLLVA SFILPIAYTW TGATIRNHPA DVVAARNKIT SRSVARSEPT NSYIRPCYFT  60
   61 NWAQYRQGRA KFVPEDYTPG LCTHILFAFG WMNADYTVRA YDPADLPNDW AGEGMYRRVN 120
  121 KLKVTDTQLK TLLSFGGWSF GTALFQGMAA SSASRKVFID SAITFVRTWG FDGIDIDWEY 180
  181 PSGATDMANY VALVKELKAA CESEAGSTGK DRLLVTAAVA AGPATIDAGY DIPNLAPNFD 240
  241 FILLMSYDFF GAWASLVGFN SPLYATTELP AEWNGWNVDS SARYWNQKGM PKEKIIVGMP 300
  301 TYGRGWTLNN ASAINPGTSG SPAKITQYVQ EAGVGAYFEF CEMLANGATR YWDSQSQVPY 360
  361 LVQGNQWWSY DDEESFANKM AYVKREGYGG AFVWTLDFDD FNAGCSNSNG QLYPLISVIA 420
  421 KELGGVIIPK KGGVTTAPTT VATTVTTGRP PMTSAVTTTT AATTTTTRAA TTTTASNTNV 480
  481 CSGKSDGFYP NSNNCGLFVL CLSSKSYSMS CPSGLQYSAS LKYCTTSTAS GCSVTTTRAP 540
  541 TTTTKSAPTV TTTTRAPTTT TPAFKCTKDG FFGVPSDCLK FIRCVNGISY NFECPNGLSF 600
  601 HADTMMCDRP DPSKCAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] PSI-BLAST 68.39794 Specificity and affinity of natural product cyclopentapeptide inhibitors against Aspergillus fumigatus, human and bacterial chitinaseFra
    2 View Details [69..532] PSI-BLAST 82.69897 Specificity and affnity of natural product cyclopentapeptide inhibitor Argadin against human chitinase
    3 View Details [533..617] PSI-BLAST 7.522879 No description for 2dtgE was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • chitinase activity
    		•  6.40555694403866 bayes_pls_golite062009
  • imaginal disc growth factor activity
    		•  3.9608908661313 bayes_pls_golite062009
  • growth factor activity
    		•  2.18932950777991 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  1.91170236789651 bayes_pls_golite062009
  • receptor binding
    		•  1.89435893935497 bayes_pls_golite062009
  • amylase activity
    		•  1.38959979746158 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  1.34796838721403 bayes_pls_golite062009
  • chitin binding
    		•  1.29046765706168 bayes_pls_golite062009
  • binding
    		•  1.1885466730171 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.80333288291596 bayes_pls_golite062009
  • glucosidase activity
    		•  0.766503513427695 bayes_pls_golite062009
  • protein binding
    		•  0.690517649847952 bayes_pls_golite062009
  • catalytic activity
    		•  0.534516847146079 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • hexosaminidase activity
    		•  0.21148675734804 bayes_pls_golite062009
  • hydrolase activity
    		•  0.178746202646272 bayes_pls_golite062009
  • pattern binding
    		•  0.113396113487931 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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