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Protein Overview: egl-43

General Information:
Name(s) found: egl-43 / CE03572 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00001207 locus:egl-43 status:Confirmed UniProt:Q22024 protein_id:CAA91353.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 543 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: collagen and cuticulin-based cuticle attachment to epithelium [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed articleLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    regulation of neuron differentiation [IMPLink to PubMed article]
    regulation of cell migration [IMPLink to PubMed article]
    regulation of transcription [TASLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    DNA binding [IEALink to PubMed article]
    transcription factor activity [ISSLink to PubMed article]
    zinc ion binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIDTDFLTS VEVKEDELHG NVLIAVTQIA LGRTIGVIDK ATPNDSNALL ILNLIKEADD  60
   61 GEDANICMRQ EDRKTFLQTS KIINIGERLL LQRLSEEECD EEDQDDLENL ILLKDEDRPD 120
  121 STQSCTKSSS EDSNLNGFEE YIREHGELVP GQTPPDGSHK CGVCPKSFSS ASGLKQHSHI 180
  181 HCSLKPFRCH LCPKSYTQFS NLCRHRRVHS DGWTCPTCQS QMPSQAALTK HRPVCEMTAL 240
  241 YKPLMAQLAG LSGAGGLGSV PYWPHILQMA TQAPHFPLAF LAANPEAYKL MQQTTCASPD 300
  301 AECSSGHASE SSPTTTEPVD LTATPKPPST SEMETTSKSD DGEDRDSIGD SGNDDDDDSE 360
  361 AGVLDESSTT TSTKKRPTSH TISDILAAPQ LGAQALNSTF LGMLQRSLNY NPAVPSPHSF 420
  421 LRAMSGAKAS SSPSSSSGSG KDRYTCKFCQ KVFPRSANLT RHLRTHTGEQ PYKCQYCERS 480
  481 FSISSNLQRH VRNIHNKPNT SLTPHNHHRQ RSLHNSTSTS TTTTTVHHPL LHLPGTSVPV 540
  541 PKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..243] PSI-BLAST 18.69897 Transcription factor IIIA, TFIIIA
    2 View Details [244..300] deduced N/A No confident structure predictions are available.
    3 View Details [301..543] PSI-BLAST 57.045757 No description for 2i13A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.14649486810497 bayes_pls_golite062009
  • DNA binding
    		•  2.89992872665011 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.66588130528088 bayes_pls_golite062009
  • transcription factor activity
    		•  1.97913234583912 bayes_pls_golite062009
  • binding
    		•  1.7678140110688 bayes_pls_golite062009
  • catalytic activity
    		•  0.616333600617445 bayes_pls_golite062009
  • transcription activator activity
    		•  0.35578487491271 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.29294316958168 bayes_pls_golite062009
  • protein binding
    		•  0.286371122239253 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle