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Protein Overview: pab-2

General Information:
Name(s) found: pab-2 / CE03230 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00003903 locus:pab-2 RNA recognition motif. (aka RRM, RBD, or RNP domain) (4 domains) status:Partially_confirmed UniProt:Q19581 protein_id:CAA90446.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 566 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: mRNA processing [IEALink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQVPPPMTQ VVTSAPPPTA AATVVAGAVA GQPQAVIQQG PPPTNIGYPP NATYSMASLY  60
   61 IGDLHPDVSE AMLFEKFSMA GPVLSIRVCR DNTSRLSLGY AYVNFQQPAD AERALDTMNF 120
  121 EVIHGRPMRI MWSQRDPAAR RAGNGNIFIK NLDRVIDNKS VYDTFSLFGN ILSCKVATDD 180
  181 EGNSKGYGFV HFETEHSAQT AIEKVNGMLL SDKKVYVGKF QPRAQRMKEL GESGLKYTNV 240
  241 FVKNFGEHLD QEKLSAMFSK FGEITSAVVM TDAQGKPKGF GFVAFADQDA AGQAVEKLND 300
  301 SILEGTDCKL SVCRAQKKSE RSAELKRKYE ALKQERVQRY QGVNLYVKNI EEDLNDDGLR 360
  361 DHFSSFGTIT SAKVMVDENG RSKGFGFVCF EKPEEATAAV TDMNSKMIGA KPLYVALAQR 420
  421 KEDRRAQLAS QYMQRLATLR MGQQASGVPA MTQLYQPGQQ GYFVPNPMNA QGRPGFQPQS 480
  481 AQIRGPPGQR VFQNQMFMQY PFNQRQVYPQ QQGRPPMRTN DGRPQYGMAP RPAGAPRVGG 540
  541 PGVQMGGAPI RQNFGVFFFF IKNLET

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..231] PSI-BLAST 48.09691 Poly(A)-binding protein
    2 View Details [232..331] PSI-BLAST 17.0 No description for 2d9pA was found.
    3 View Details [332..435] FFAS03 5.47 No description for 2f3jA was found.
    4 View Details [436..566] PSI-BLAST 3.69897 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  6.73097473547076 bayes_pls_golite062009
    		• 6.62953239642182 bayes_pls_golite062009
  • mRNA binding
    		•  5.29759606920196 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • snRNA binding
    		•  4.06596327298973 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  3.11990160533699 bayes_pls_golite062009
  • U1 snRNA binding
    		•  3.02511982045347 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  2.93798024346416 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • protein binding
    		•  2.17260848225967 bayes_pls_golite062009
  • DNA binding
    		•  1.98418556946403 bayes_pls_golite062009
  • structural molecule activity
    		•  1.56454315220334 bayes_pls_golite062009
  • U2 snRNA binding
    		•  1.34078165372485 bayes_pls_golite062009
  • transcription factor activity
    		•  1.07843408116687 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.824614388276642 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.632534695085793 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.100880394187931 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.0459458211377304 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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